{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T02:59:12Z","timestamp":1776135552780,"version":"3.50.1"},"reference-count":5,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2021,7,8]],"date-time":"2021-07-08T00:00:00Z","timestamp":1625702400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Synovial sarcoma is a soft tissue sarcoma. Its occurrence as a primary mediastinal neoplasm is very rare. We report a case of mediastinal synovial sarcoma in a 14\u2010year\u2010old girl with exertive dyspnoea at presentation. On physical examination, there was a superior vena cava syndrome and caf\u00e9\u2010au\u2010lait spots. Chest X\u2010ray revealed a white left hemithorax with mediastinal deviation to the opposite side. Thoraco\u2010abdomino\u2010pelvic scanner showed a voluminous posterior cervico\u2010mediastinal tissue mass. Computed tomography (CT)\u2010guided biopsy of the mediastino\u2010pleural mass was performed. Histological examination reported fusocellular malignant mesenchymal proliferation. A complementary immunohistological study with a broad range of antibodies was performed with a high\u2010grade single\u2010phase spindle cell synovial sarcoma of the mediastinum. She presented a respiratory distress, did not respond to resuscitation, and died. Mediastinal synovial sarcoma is a rare tumour that is difficult to diagnose. Its slow progression and delay in diagnosis may lead to a fatal evolution.<\/jats:p>","DOI":"10.1002\/rcr2.811","type":"journal-article","created":{"date-parts":[[2021,7,8]],"date-time":"2021-07-08T10:46:40Z","timestamp":1625741200000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Primary synovial sarcoma of the mediastinum: a poor prognosis in a 14\u2010year\u2010old girl"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8812-4902","authenticated-orcid":false,"given":"Asma","family":"Saad","sequence":"first","affiliation":[{"name":"Thoracic and Cardiovascular Surgery Department Abderrahmen Mami Hospital  Ariana Tunisia 2080 Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Imen","family":"Bouacida","sequence":"additional","affiliation":[{"name":"Thoracic and Cardiovascular Surgery Department Abderrahmen Mami Hospital  Ariana Tunisia 2080 Tunisia"},{"name":"Thoracic surgery department EL Manar University, Farhat Hached University Campus  Tunis Tunisia 1068 Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bechir","family":"Ben Radhia","sequence":"additional","affiliation":[{"name":"Thoracic and Cardiovascular Surgery Department Abderrahmen Mami Hospital  Ariana Tunisia 2080 Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hazem","family":"Zribi","sequence":"additional","affiliation":[{"name":"Thoracic and Cardiovascular Surgery Department Abderrahmen Mami Hospital  Ariana Tunisia 2080 Tunisia"},{"name":"Thoracic surgery department EL Manar University, Farhat Hached University Campus  Tunis Tunisia 1068 Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amira","family":"Dridi","sequence":"additional","affiliation":[{"name":"Thoracic surgery department EL Manar University, Farhat Hached University Campus  Tunis Tunisia 1068 Tunisia"},{"name":"Anesthesia Reanimation Department Abderrahmen Mami Hospital  Ariana Tunisia 2080 Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adel","family":"Marghli","sequence":"additional","affiliation":[{"name":"Thoracic and Cardiovascular Surgery Department Abderrahmen Mami Hospital  Ariana Tunisia 2080 Tunisia"},{"name":"Thoracic surgery department EL Manar University, Farhat Hached University Campus  Tunis Tunisia 1068 Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,7,8]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.4103\/0973-1482.77075"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.3892\/ol.2013.1649"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.4076\/1757-1626-2-6948"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-200003000-00011"},{"key":"e_1_2_4_6_1","first-page":"109","article-title":"Primary mediastinal synovial sarcoma","volume":"76","author":"Jeganathan R","year":"2007","journal-title":"Ulster Med. J."}],"container-title":["Respirology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.811","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/rcr2.811","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.811","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,30]],"date-time":"2023-08-30T00:19:31Z","timestamp":1693354771000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/rcr2.811"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7,8]]},"references-count":5,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2021,8]]}},"alternative-id":["10.1002\/rcr2.811"],"URL":"https:\/\/doi.org\/10.1002\/rcr2.811","archive":["Portico"],"relation":{},"ISSN":["2051-3380","2051-3380"],"issn-type":[{"value":"2051-3380","type":"print"},{"value":"2051-3380","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,7,8]]},"assertion":[{"value":"2021-02-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-06-22","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-07-08","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00811"}}