{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T10:09:51Z","timestamp":1753870191486,"version":"3.41.2"},"reference-count":5,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2021,8,16]],"date-time":"2021-08-16T00:00:00Z","timestamp":1629072000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Primary central nervous system neuroblastoma (PCNS\u2010NBL) is a rare and aggressive malignant tumour. Pleural metastases of PCNS\u2010NBL have not been documented before. We report a case of a 30\u2010year\u2010old male patient, with a history of PCNS\u2010NBL treated with surgery, radiation and chemotherapy. Three years later, he presented an aggravated dyspnoea with impaired general condition. The different investigations confirmed that his PCNS\u2010NBL has relapsed with bone, lymph nodes and bilateral pleural metastases. Because of the disseminated disease and the poor general condition of the patient, only symptomatic treatment measures were preconized. The patient died 3\u2009months later following cardiorespiratory arrest. To the best of our knowledge, this is the first case reporting bilateral pleural metastases of a PCNS\u2010NBL in a young adult.<\/jats:p>","DOI":"10.1002\/rcr2.829","type":"journal-article","created":{"date-parts":[[2021,8,16]],"date-time":"2021-08-16T09:32:03Z","timestamp":1629106323000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Bilateral pleural metastases of a primary central nervous system neuroblastoma in an adult: First case in the world"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6921-9658","authenticated-orcid":false,"given":"Lobna","family":"Loued","sequence":"first","affiliation":[{"name":"Pneumology Department Fattouma Bourguiba Hospital of Monastir  Monastir Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asma","family":"Migaou","sequence":"additional","affiliation":[{"name":"Pneumology Department Fattouma Bourguiba Hospital of Monastir  Monastir Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mabrouk","family":"Abdelaaly","sequence":"additional","affiliation":[{"name":"Radiology Department Fattouma Bourguiba Hospital of Monastir  Monastir Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahlem","family":"Bellalah","sequence":"additional","affiliation":[{"name":"Pathology Department Fattouma Bourguiba Hospital of Monastir  Monastir Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nesrine","family":"Fahem","sequence":"additional","affiliation":[{"name":"Pneumology Department Fattouma Bourguiba Hospital of Monastir  Monastir Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rania","family":"Kaddoussi","sequence":"additional","affiliation":[{"name":"Pneumology Department Fattouma Bourguiba Hospital of Monastir  Monastir Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9841-9210","authenticated-orcid":false,"given":"Ahmed","family":"Ben Saad","sequence":"additional","affiliation":[{"name":"Pneumology Department Fattouma Bourguiba Hospital of Monastir  Monastir Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samah","family":"Joobeur","sequence":"additional","affiliation":[{"name":"Pneumology Department Fattouma Bourguiba Hospital of Monastir  Monastir Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saoussen","family":"Cheikh Mhamed","sequence":"additional","affiliation":[{"name":"Pneumology Department Fattouma Bourguiba Hospital of Monastir  Monastir Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naceur","family":"Rouatbi","sequence":"additional","affiliation":[{"name":"Pneumology Department Fattouma Bourguiba Hospital of Monastir  Monastir 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