{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T15:08:17Z","timestamp":1761491297600,"version":"3.41.2"},"reference-count":7,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2021,10,12]],"date-time":"2021-10-12T00:00:00Z","timestamp":1633996800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A 63\u2010year\u2010old female presented with chest pain and fever, and was found to have recurrent pleuropericardial effusions. Extensive investigations including infection screen and serologies, autoimmune screen and pleural and pericardial biopsy revealed no secondary aetiologies. She was diagnosed with idiopathic recurrent serositis (IRS). Our patient developed rash to naproxen, so she was started on colchicine monotherapy and responded well clinically. A review of the literature demonstrated that pleuropericardial effusions are rare occurrences, with patients occasionally being perceived as a medical enigma. This case study recommends an approach to guide physicians in their diagnosis and management of patients with pleuropericardial syndrome. Our case had an inflammatory phenotype, either autoimmune or seronegative serositis of unclear aetiology, which was recurrent and required pharmacological treatment. While the treatment for IRS lies in combined therapy with Nonsteroidal Anti\u2010Inflammatory Drugs (NSAIDs) and colchicine, monotherapy with colchicine was effective in the treatment and preventing recurrence in our unique case.<\/jats:p>","DOI":"10.1002\/rcr2.859","type":"journal-article","created":{"date-parts":[[2021,10,12]],"date-time":"2021-10-12T13:52:50Z","timestamp":1634046770000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Idiopathic recurrent serositis\u2014Off the beaten track"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3939-599X","authenticated-orcid":false,"given":"Melanie Trishna Hui Min","family":"Roy","sequence":"first","affiliation":[{"name":"Undergraduate Medicine National University of Ireland  Galway Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chee Hong","family":"Loh","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine Changi General Hospital  Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melonie","family":"Sriranganathan","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine Changi General Hospital  Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela Maria","family":"Takano Pena","sequence":"additional","affiliation":[{"name":"Department of Pathology Singapore General Hospital  Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jagadesan","family":"Raghuram","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine Changi General Hospital  Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,10,12]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.0020063"},{"key":"e_1_2_7_3_1","first-page":"3352","article-title":"Therapeutic management of idiopathic recurrent serositis: a retrospective study","volume":"6","author":"Massaro M","year":"2020","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/crj.12940"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1159\/000083404"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehi197"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.111.066365"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1183\/20734735.0203-2020"}],"container-title":["Respirology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.859","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/rcr2.859","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.859","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,28]],"date-time":"2023-08-28T02:32:58Z","timestamp":1693189978000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/rcr2.859"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10,12]]},"references-count":7,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2021,11]]}},"alternative-id":["10.1002\/rcr2.859"],"URL":"https:\/\/doi.org\/10.1002\/rcr2.859","archive":["Portico"],"relation":{},"ISSN":["2051-3380","2051-3380"],"issn-type":[{"type":"print","value":"2051-3380"},{"type":"electronic","value":"2051-3380"}],"subject":[],"published":{"date-parts":[[2021,10,12]]},"assertion":[{"value":"2021-06-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-09-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-10-12","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e0859"}}