{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T21:02:48Z","timestamp":1763154168606,"version":"3.41.2"},"reference-count":16,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,1,25]],"date-time":"2022-01-25T00:00:00Z","timestamp":1643068800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Humidified rapid\u2010insufflation ventilatory exchange (HRIVE) is an option for maintenance of oxygenation. This technique allows for oxygenation while the patient is apnoeic due to continuous positive airway pressure and gas exchange through flow\u2010dependent dead space flushing. There is no study about the usage of HRIVE during rigid bronchoscopy. This retrospective study looked at rigid bronchoscopy cases utilizing HRIVE. Data points assessing adequacy of oxygenation and ventilation were recorded at time points: oxygen saturation (SpO<jats:sub>2<\/jats:sub>), partial pressure of oxygen (PaO<jats:sub>2<\/jats:sub>) and partial pressure of carbon dioxide (PaCO<jats:sub>2<\/jats:sub>). Our nine cases had an average baseline SpO<jats:sub>2<\/jats:sub> of 99.26%, 95.56% at 10\u00a0min into HRIVE and 95.27% at the end of HRIVE. The average baseline PaO<jats:sub>2<\/jats:sub> was 309.01\u2009mmHg, 124.99\u2009mmHg at 10\u00a0min into HRIVE and 128.17\u2009mmHg at the end of HRIVE. The average baseline PaCO<jats:sub>2<\/jats:sub> was 43.26\u2009mmHg, 68.76\u2009mmHg at 10\u00a0min into HRIVE and 75.52\u2009mmHg at the end of HRIVE. The average pre\u2010HRIVE end\u2010tidal CO<jats:sub>2<\/jats:sub> (ETCO<jats:sub>2<\/jats:sub>) was 38.56\u2009mmHg and the average post\u2010HRIVE ETCO<jats:sub>2<\/jats:sub> was 61.22\u2009mmHg. The average baseline pH was 7.36, 7.22 at 10\u00a0min into HRIVE and 7.19 at the end of HRIVE. In this small cohort study, HRIVE was able to maintain adequate oxygenation via the rigid bronchoscope in a select group of patients. Hypercapnia and respiratory acidosis did result after 10\u00a0min, which may predispose certain patient populations to complications. HRIVE potentially offers an additional option of oxygenation via the rigid bronchoscope.<\/jats:p>","DOI":"10.1002\/rcr2.903","type":"journal-article","created":{"date-parts":[[2022,1,26]],"date-time":"2022-01-26T07:45:15Z","timestamp":1643183115000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Humidified <scp>rapid\u2010insufflation<\/scp> ventilatory exchange is a means of oxygenation during rigid bronchoscopy: A case series"],"prefix":"10.1002","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8929-2131","authenticated-orcid":false,"given":"Anna","family":"Kornafeld","sequence":"first","affiliation":[{"name":"Division of Pulmonary and Critical Care, Department of Medicine Mayo Clinic Jacksonville  Jacksonville Florida 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M.","family":"Chadha","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Perioperative Medicine Mayo Clinic Jacksonville  Jacksonville Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,1,25]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/4234861"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/anae.14215"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/anae.12923"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/coa.13447"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/coa.13408"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.4103\/ija.IJA_717_17"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-197312000-00006"},{"key":"e_1_2_7_9_1","first-page":"366","article-title":"Respiratory acidosis","volume":"46","author":"Epstein 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