{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T22:07:41Z","timestamp":1759010861793,"version":"3.41.2"},"reference-count":5,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2022,3,8]],"date-time":"2022-03-08T00:00:00Z","timestamp":1646697600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A 79\u2010year\u2010old former smoking Japanese man was admitted to our hospital with a 2\u2010year history of dry cough and dyspnoea on exertion. High\u2010resolution computed tomography of the chest revealed reticulation and perilobular opacity with bronchial wall thickening and ground\u2010glass opacities (GGOs) in both lungs, in addition to subpleural dense consolidation (pleuroparenchymal fibroelastosis\u2010like lesion; PPFE\u2010like lesion) predominantly in the bilateral upper lobes. Serum immunoglobulin G4 (IgG4) was elevated (348\u2009mg\/dl). Lung biopsy specimens obtained by video\u2010assisted surgery revealed a mixture of usual interstitial pneumonia (IP) and non\u2010specific IP pattern admixed with PPFE. In addition, immunohistochemical staining of IgG4 showed numerous IgG4\u2010positive plasma cells. Consequently, he was diagnosed with IgG4\u2010positive IP associated with PPFE. We initiated a combination therapy with prednisolone and cyclosporine as a calcineurin inhibitor. During prednisolone tapering, his clinical conditions and GGOs improved gradually over 12\u2009months. However, reticular opacities and PPFE\u2010like lesions remained unchanged, and pulmonary function test findings slightly deteriorated.<\/jats:p>","DOI":"10.1002\/rcr2.925","type":"journal-article","created":{"date-parts":[[2022,3,8]],"date-time":"2022-03-08T08:04:53Z","timestamp":1646726693000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Immunoglobulin <scp>G4<\/scp>\u2010positive interstitial pneumonia associated with pleuroparenchymal fibroelastosis"],"prefix":"10.1002","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3688-6782","authenticated-orcid":false,"given":"Keishi","family":"Sugino","sequence":"first","affiliation":[{"name":"Department of Respiratory Medicine Tsuboi Hospital  Koriyama City Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9090-506X","authenticated-orcid":false,"given":"Hirotaka","family":"Ono","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Tsuboi Hospital  Koriyama City Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mikako","family":"Saito","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Tsuboi Hospital  Koriyama City Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seiji","family":"Igarashi","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Pathology Tsuboi Hospital  Koriyama City Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atsuko","family":"Kurosaki","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology Fukujuji Hospital, Anti\u2010tuberculosis Association  Kiyose City Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eiyasu","family":"Tsuboi","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Tsuboi Hospital  Koriyama City Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,3,8]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.3109\/s10165-011-0571-z"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/his.13053"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.11-1858"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmcr.2018.09.017"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1183\/23120541.00317-2021"}],"container-title":["Respirology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.925","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/rcr2.925","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.925","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,25]],"date-time":"2023-08-25T12:19:52Z","timestamp":1692965992000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/rcr2.925"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,8]]},"references-count":5,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022,4]]}},"alternative-id":["10.1002\/rcr2.925"],"URL":"https:\/\/doi.org\/10.1002\/rcr2.925","archive":["Portico"],"relation":{},"ISSN":["2051-3380","2051-3380"],"issn-type":[{"type":"print","value":"2051-3380"},{"type":"electronic","value":"2051-3380"}],"subject":[],"published":{"date-parts":[[2022,3,8]]},"assertion":[{"value":"2021-12-01","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-02-20","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-03-08","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e0925"}}