{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T17:01:17Z","timestamp":1764349277541,"version":"3.41.2"},"reference-count":24,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,12,11]],"date-time":"2022-12-11T00:00:00Z","timestamp":1670716800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Robotics Computer Surgery"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>How to precisely protect and preserve anterior and posterior vagal trunks and all their branches during the procedure of splenectomy and azygoportal disconnection is studied rarely. We firstly developed a vagus nerve\u2010guided robotic\u2010assisted laparoscopic splenectomy and azygoportal disconnection (VGRSD). The aim of this study was to evaluate whether VGRSD is feasible and safe and to determine whether VGRSD can effectively eliminate postoperative digestive system complications by protecting vagal nerve precisely.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>In this prospective clinical study, 10 cirrhotic patients with oesophagogastric variceal bleeding and hypersplenism who underwent VGRSD between January 2022 and March 2022 were gathered, and compared with a retrospective cohort who received a part of the vagus nerve\u2010preserving robotic\u2010assisted laparoscopic splenectomy and azygoportal disconnection (VPRSD). They were all followed up for 6\u00a0months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In VGRSD group, the operation time was 173.5\u00a0\u00b1\u00a016.2\u00a0min, blood loss was 68.0\u00a0\u00b1\u00a039.1\u00a0ml, VAS pain score on the first day was 1.9\u00a0\u00b1\u00a00.7, and the postoperative hospital stay was 7.7\u00a0\u00b1\u00a00.7\u00a0days. There was no incisional complications, pneumonia, gastric fistula, pancreatic fistula, and abdominal infection. No patients suffered from diarrhoea, delayed gastric emptying, and epigastric fullness. Compared with VPRSD, operation time was significantly longer for VGRSD (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.05). However, VGRSD was significantly associated with less diarrhoea and shorter postoperative hospital stay (all <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>VGRSD procedure is not only technically feasible and safe, it also effectively eliminate postoperative digestive system complications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Trial registration<\/jats:title><jats:p>We registered our research at <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"https:\/\/www.clinicaltrials.gov\/\">https:\/\/www.clinicaltrials.gov\/<\/jats:ext-link>. The name of research registered is \u2018Vagus Nerve\u2010guided Robotic\u2010assisted Splenectomy and Azygoportal Disconnection\u2019. The trial registration identifier at <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/clinicaltrials.gov\">clinicaltrials.gov<\/jats:ext-link> is NCT05300516.<\/jats:p><\/jats:sec>","DOI":"10.1002\/rcs.2490","type":"journal-article","created":{"date-parts":[[2022,12,7]],"date-time":"2022-12-07T20:26:50Z","timestamp":1670444810000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Vagus nerve\u2010guided (modified Bai\u2010Jiang\u2010style) robotic\u2010assisted laparoscopic splenectomy and azygoportal disconnection"],"prefix":"10.1002","volume":"19","author":[{"given":"Dou\u2010Sheng","family":"Bai","sequence":"first","affiliation":[{"name":"Department of Hepatobiliary Surgery Clinical Medical College Yangzhou University  Yangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sheng\u2010Jie","family":"Jin","sequence":"additional","affiliation":[{"name":"Department of Hepatobiliary Surgery Clinical Medical College Yangzhou University  Yangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bao\u2010Huan","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Hepatobiliary Surgery Clinical Medical College Yangzhou University  Yangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao\u2010Xing","family":"Xiang","sequence":"additional","affiliation":[{"name":"Department of Digestive Diseases Clinical Medical College Yangzhou University  Yangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian\u2010Jun","family":"Qian","sequence":"additional","affiliation":[{"name":"Department of Hepatobiliary Surgery Clinical Medical College Yangzhou University  Yangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chi","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Hepatobiliary Surgery Clinical Medical College Yangzhou University  Yangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tian\u2010Ming","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of Hepatobiliary Surgery Clinical Medical College Yangzhou University  Yangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8699-6624","authenticated-orcid":false,"given":"Guo\u2010Qing","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Hepatobiliary Surgery Clinical Medical College Yangzhou University  Yangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,12,11]]},"reference":[{"key":"e_1_2_11_2_1","first-page":"232","article-title":"Gastroesophageal decongestion and splenectomy. 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