{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T10:09:53Z","timestamp":1753870193392,"version":"3.41.2"},"reference-count":38,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,3,30]],"date-time":"2023-03-30T00:00:00Z","timestamp":1680134400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Robotics Computer Surgery"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>This study suggested a novel physiological evaluation of indocyanine\u2010green fluorescence imaging (IFI), and its utility associated with anastomotic leakage\/stricture (AL\/AS) and prognosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This study focussed on the utility of IFI, comparing IFI\u00a0+\u00a0versus IFI\u2010 groups (<jats:italic>n<\/jats:italic>\u00a0=\u00a0878 vs. 339), optimised by propensity\u2010score matching. After intravenous injection of indocyanine green, maximal perfusion was separately assessed at the vasa recta (VR) and colonic wall (CW), by determining intensities at the VR (VRI) and CW (CWI) and respective time.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Although IFI did not significantly reduce either AL or AS, which occurred approximately 3\u2010fold frequently in patients with lower than higher intensity of VRI. IFI was found as an independent parameter for both disease\u2010free [DFS: hazard ratio (HR)\u00a0=\u00a00.489; <jats:italic>p<\/jats:italic>\u00a0=\u00a00.002] and overall survival (OS: HR\u00a0=\u00a00.519; <jats:italic>p<\/jats:italic>\u00a0=\u00a00.021).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Although IFI did not significantly reduce AL\/AS, IFI independently reduced 5\u2010year systemic recurrence and increased 5\u2010year DFS and OS.<\/jats:p><\/jats:sec>","DOI":"10.1002\/rcs.2515","type":"journal-article","created":{"date-parts":[[2023,3,30]],"date-time":"2023-03-30T11:23:28Z","timestamp":1680175408000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Interpretation and clinical utility of indocyanine\u2010green fluorescence imaging (IFI) in robot\u2010assisted anorectal\u2010function saving operations (ASOs): A propensity\u2010score matched analysis of 872 prospectively enroled patients undergoing IFI"],"prefix":"10.1002","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4823-8619","authenticated-orcid":false,"given":"Jin Cheon","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Surgery Division of Colorectal Surgery University of Ulsan College of Medicine and Asan Medical Center  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5878-8000","authenticated-orcid":false,"given":"Jong Lyul","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Surgery Division of Colorectal Surgery University of Ulsan College of Medicine and Asan Medical Center  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2382-0939","authenticated-orcid":false,"given":"Chan Wook","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Surgery Division of Colorectal Surgery University of 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