{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T01:52:36Z","timestamp":1788573156598,"version":"build-2803163510"},"reference-count":39,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,3,10]],"date-time":"2025-03-10T00:00:00Z","timestamp":1741564800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["No. 2018YFE0206900"],"award-info":[{"award-number":["No. 2018YFE0206900"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Robotics Computer Surgery"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Robotic systems are increasingly utilised to improve clinical outcomes in prostate interventions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We enroled 20 patients to verify the clinical feasibility of transrectal ultrasound (TRUS)\u2010guided robot\u2010assisted prostate biopsy (PBx). For each patient, controlled trials of systematic 12\u2010core PBx were initially conducted manually using a biopsy gun, followed by a 3\u2010core cognitive fusion targeted biopsy performed by the hand\u2010held robot.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The targeting errors for robot\u2010assisted biopsy and freehand biopsy were 3.71\u00a0\u00b1\u00a01.41\u00a0mm and 3.94\u00a0\u00b1\u00a01.49\u00a0mm, respectively. Their cancer core rates were 19.1% and 12.6%, and the average duration of each biopsy was 6.94 min and 1.62\u00a0min, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The robot's sampling success rate was lower than that of freehand with a biopsy gun in the clinical trial. However, robot\u2010assisted PBx has shown improved cancer core rate, slightly enhanced surgical accuracy, and the capability to reach clinically significant tumours' 5\u00a0mm error range, all demonstrating its clinical value.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/rcs.70062","type":"journal-article","created":{"date-parts":[[2025,3,12]],"date-time":"2025-03-12T04:12:13Z","timestamp":1741752733000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Safety and Efficacy Clinical Trial of Robot\u2010Assisted Prostate Biopsy Using a Hand\u2010Held Robotic System"],"prefix":"10.1002","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5315-7288","authenticated-orcid":false,"given":"Wenhe","family":"Jiang","sequence":"first","affiliation":[{"name":"State Key Laboratory of Robotics and System Department of Mechanical Engineering Harbin Institute of Technology  Harbin 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