{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T20:44:32Z","timestamp":1776199472730,"version":"3.50.1"},"reference-count":32,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2017,8,21]],"date-time":"2017-08-21T00:00:00Z","timestamp":1503273600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Reprod Medicine &amp; Biology"],"published-print":{"date-parts":[[2017,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To investigate the impact of adenomyosis on the complications and outcomes of pregnancy in Japan.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We carried out a multicenter retrospective questionnaire survey. A questionnaire regarding pregnancy complications and the outcomes of pregnancy was sent to 725 facilities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Data were obtained on the cases of 272 pregnant women with adenomyosis from 65 facilities. The complications of pregnancy included miscarriage before 12\u00a0weeks of pregnancy (14.8%), miscarriage after 12\u00a0weeks of pregnancy (9.9%), preterm delivery (24.4%), fetal growth restriction (11.8%), pregnancy\u2010induced hypertension (9.9%), intrauterine infection (7.3%), and cervical incompetency (5.3%). The rates of pregnancy complications in the three groups classified according to pretreatment for adenomyosis (no pretreatment, medication, surgery) did not differ to a statistically significant extent. The rates of miscarriage (&gt;12\u00a0weeks) and cervical incompetency increased according to the size of the adenomyosis. The rates of pregnancy\u2010induced hypertension and uterine infection in patients with diffuse\u2010type adenomyosis were higher than that in patients with focal\u2010type adenomyosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our results show that the increased size and diffuse type of adenomyosis are associated with adverse pregnancy outcome. We should be aware of the higher incidence of pregnancy\u2010induced hypertension and uterine infection in patients with diffuse\u2010type adenomyosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/rmb2.12050","type":"journal-article","created":{"date-parts":[[2017,8,21]],"date-time":"2017-08-21T21:19:07Z","timestamp":1503350347000},"page":"330-336","source":"Crossref","is-referenced-by-count":55,"title":["Complications and outcomes of pregnant women with adenomyosis in Japan"],"prefix":"10.1002","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6258-4572","authenticated-orcid":false,"given":"Hiroshi","family":"Tamura","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Yamaguchi University Graduate School of Medicine  Ube Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Kishi","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Gunma University Graduate School of Medicine  Maebashi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mari","family":"Kitade","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Juntendo University School of Medicine  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mikiko","family":"Asai\u2010Sato","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Yokohama City University Hospital  Yokohama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5299-2505","authenticated-orcid":false,"given":"Atsushi","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Saint Mother Obstetrics and Gynecology Clinic Institute for ART  Fukuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Murakami","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Shiga University of Medical Science  Otsu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Minegishi","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Gunma University Graduate School of Medicine  Maebashi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norihiro","family":"Sugino","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Yamaguchi University Graduate School of Medicine  Ube Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,8,21]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1472-6483(10)60535-4"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2006.01186.x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jog.12604"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dep474"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpobgyn.2006.01.016"},{"key":"e_1_2_7_7_1","first-page":"224","article-title":"Adenomyosis in pregnancy. 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