{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T22:20:44Z","timestamp":1762899644273,"version":"3.40.5"},"reference-count":14,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,11,29]],"date-time":"2018-11-29T00:00:00Z","timestamp":1543449600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Health and Labour Sciences Research Grants","award":["H30-Sukoyaka-Ippan-002"],"award-info":[{"award-number":["H30-Sukoyaka-Ippan-002"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Reprod Medicine &amp; Biology"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>The Japan Society of Obstetrics and Gynecology started an online cycle\u2010based assisted reproductive technology (ART) registry system in 2007. This report presents the characteristics and treatment outcomes of ART registered for the cycles practiced during 2016.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Cycle\u2010specific information for all ART cycles implemented in participating ART facilities were collected. A descriptive analysis was conducted for the registry database of 2016.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In total, 447\u00a0790 treatment cycles and 54\u00a0110 neonates (one in 18.1 neonates born in Japan) were reported in 2016. The mean patients\u2019 age was 38.1\u00a0years (SD\u00a0=\u00a04.5). Among the egg retrieval cycles, 104\u00a0575 of 251\u00a0399 (41.6%) were freeze\u2010all cycles without fresh embryo transfers (ET), while fresh ET was performed in 64\u00a0497 cycles (58.4%). A total of 187\u00a0132 frozen\u2010thawed ET cycles were reported, resulting in 62\u00a0432 pregnancies and 44\u00a0484 neonates born. Single ET was selected for 81.0% of fresh transfers and 82.7% of frozen cycles, resulting in singleton pregnancy\/live birth rates of 97.0%\/96.4% and 96.7%\/96.4%, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The total ART cycles and subsequent live births continued to increase in 2016. Single ET was performed more than 80%, and ET has shifted from using fresh embryos to frozen ones.<\/jats:p><\/jats:sec>","DOI":"10.1002\/rmb2.12258","type":"journal-article","created":{"date-parts":[[2018,11,30]],"date-time":"2018-11-30T07:51:10Z","timestamp":1543564270000},"page":"7-16","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Assisted reproductive technology in Japan: A summary report for 2016 by the Ethics Committee of the Japan Society of Obstetrics and Gynecology"],"prefix":"10.1002","volume":"18","author":[{"given":"Osamu","family":"Ishihara","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Saitama Medical University Saitama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8815-5714","authenticated-orcid":false,"given":"Seung Chik","family":"Jwa","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Saitama Medical University Saitama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akira","family":"Kuwahara","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Graduate School of Biomedical Sciences Tokushima University Tokushima Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1012-1557","authenticated-orcid":false,"given":"Tomonori","family":"Ishikawa","sequence":"additional","affiliation":[{"name":"Department of Comprehensive Reproductive Medicine, Graduate School Tokyo Medical and Dental University Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koji","family":"Kugu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Tokyo Metropolitan Bokutoh Hospital Tokyo 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Medicine National Center for Child Health and Development Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,11,29]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dew082"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/rmb2.12074"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/rmb2.12014"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmq028"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10815-014-0181-8"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2015.10.002"},{"key":"e_1_2_8_8_1","first-page":"CD012103","article-title":"Interventions for the prevention of OHSS in ART cycles: an overview of Cochrane reviews","volume":"1","author":"Mourad S","year":"2017","journal-title":"Cochrane Database Syst 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