{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T05:35:41Z","timestamp":1790832941075,"version":"4.1.0"},"reference-count":29,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,1,4]],"date-time":"2023-01-04T00:00:00Z","timestamp":1672790400000},"content-version":"vor","delay-in-days":3,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Reprod Medicine &amp; Biology"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Since 1986, the Japan Society of Obstetrics and Gynecology assisted reproductive technology (ART) registry system has collected data on national ART use and outcomes trends in Japan. Herein, we describe the characteristics and outcomes of ART cycles registered during 2020 and compare the results with those from 2019.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and Results<\/jats:title>\n                    <jats:p>In 2020, 621 ART facilities participated in the registration. The total number of registered cycles was 449\u2009900, and there were 60\u2009381 live births, which decreased from the previous year (1.79% and 0.36% decrease, respectively). The number of freeze\u2010all in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) cycles increased in 2020, and the number of neonates born was 2282 for IVF\u2010embryo transfer (ET) cycles and 2596 for ICSI cycles, which had decreased from the previous year. Frozen\u2013thawed ET (FET) cycles had slightly increased from 2019 (0.04%). In 2020, 215\u2009285 FET cycles were conducted, resulting in 76\u2009196 pregnancies and 55\u2009503 neonates. Single ET was performed in 81.6% of fresh transfers and 85.1% of frozen\u2013thawed cycles, respectively, resulting in over 97% singleton pregnancies\/livebirths rates.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Despite the COVID\u201019 pandemic during 2020, the overall number of ART cycles and neonates born demonstrated only a slight decrease in 2020 compared with 2019.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/rmb2.12494","type":"journal-article","created":{"date-parts":[[2023,1,4]],"date-time":"2023-01-04T08:55:25Z","timestamp":1672822525000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":52,"title":["Assisted reproductive technology in Japan: A summary report for 2020 by the ethics Committee of the Japan Society of obstetrics and gynecology"],"prefix":"10.1002","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0052-896X","authenticated-orcid":false,"given":"Yukiko","family":"Katagiri","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Faculty of Medicine Toho University  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8815-5714","authenticated-orcid":false,"given":"Seung Chik","family":"Jwa","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Saitama Medical University  Saitama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akira","family":"Kuwahara","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Graduate School of Biomedical Sciences Tokushima University  Tokushima Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1014-5687","authenticated-orcid":false,"given":"Takeshi","family":"Iwasa","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Graduate School of Biomedical Sciences Tokushima University  Tokushima Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masanori","family":"Ono","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Tokyo Medical University  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keiichi","family":"Kato","sequence":"additional","affiliation":[{"name":"Kato Ladies Clinic  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1562-410X","authenticated-orcid":false,"given":"Hiroshi","family":"Kishi","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology The Jikei University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1622-4063","authenticated-orcid":false,"given":"Yoshimitsu","family":"Kuwabara","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Nippon Medical School  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1071-5600","authenticated-orcid":false,"given":"Miyuki","family":"Harada","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Graduate School of Medicine The University of Tokyo  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshio","family":"Hamatani","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology School of Medicine, Keio University  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yutaka","family":"Osuga","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Graduate School of Medicine The University of Tokyo  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,1,4]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deab198"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/rmb2.12434"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/rmb2.12358"},{"key":"e_1_2_12_5_1","volume-title":"Handbook of health and welfare statistics 2021 contents","author":"Ministry of Health, Labour and Welfare of Japan","year":"2022"},{"key":"e_1_2_12_6_1","unstructured":"The World Bank.Fertility rate total (births per woman) 2021. 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