{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T15:14:28Z","timestamp":1786634068068,"version":"build-2736575974"},"reference-count":21,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,9,9]],"date-time":"2024-09-09T00:00:00Z","timestamp":1725840000000},"content-version":"vor","delay-in-days":252,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP22498963"],"award-info":[{"award-number":["JP22498963"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP18K19618"],"award-info":[{"award-number":["JP18K19618"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Reprod Medicine &amp; Biology"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>Several studies investigated endometrial patterns, with respect to pregnancy rates following the transfer of embryos but did not distinguish between single\u2010 and multiple\u2010blastocyst procedures. We clarified how the endometrial pattern imaged to transfer a frozen embryo is associated with pregnancy outcomes in single\u2010blastocyst frozen\u2010embryo transfer (sbFET).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients \u226435\u2009years who underwent sbFET on the hormone replacement protocol. We analyzed endometrial patterns\u2019 associations with pregnancy outcomes in relation to blastocyst grade and pregnancy\u2010related factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 1383\u2009cycles, 483 were Lf, 840 were partial\u2010Lf, and 60 were non\u2010Lf. Leaf pattern (Lf): central echogenic line present and continuous. Overall, decreasing distinctness of the central echogenic line was associated with significantly lower rates of clinical pregnancy (Lf: 70.4%; partial\u2010Lf: 58.1%; non\u2010Lf: 28.3%) and live birth (56.3%, 45.5%, and 15.0%) and a higher miscarriage rate (20.0%, 21.7%, and 47.1%). Logistic regressions showed pregnancy and live birth to be significantly more likely and miscarriage less likely in Lf than non\u2010Lf: OR (95% CI): 6.07 (3.24\u201311.37), 7.43 (3.47\u201315.39), and 0.20 (0.07\u20130.57).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Non\u2010Lf presentation was associated with lower rates of pregnancy and live birth, suggesting it signals unsuitable conditions for embryo transfer. We provide information on the pregnancy outcomes of sbFET for endometrial patterns.<\/jats:p><\/jats:sec>","DOI":"10.1002\/rmb2.12599","type":"journal-article","created":{"date-parts":[[2024,9,10]],"date-time":"2024-09-10T05:39:44Z","timestamp":1725946784000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Endometrial pattern predicts pregnancy outcome in single\u2010blastocyst frozen\u2010embryo transfer: An analysis of 1383\u2009cycles"],"prefix":"10.1002","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-8827-0222","authenticated-orcid":false,"given":"Kazutaka","family":"Kuramoto","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Graduate School of Medical Sciences Kyushu University  Fukuoka Japan"},{"name":"Kuramoto Women's Clinic  Fukuoka 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