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In addition to maternal age, controlled ovarian hyperstimulation (COH) protocols also play a key role in affecting the quality of the egg. After egg retrieval, the insemination occurs 3\u20136\u2009h after collection, with a pre\u2010IVF incubation time by in\u00a0vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) (39\u201342\u2009h post\u2010HCG injection). The pre\u2010IVF incubation refers to the short period time of 3 to 6\u2009h after oocyte retrieval and before the insemination by IVF or ICSI. The pre\u2010IVF incubation of collected eggs in the designed culture medium improves egg quality in terms of maturation and early embryonic development.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Pre\u2010IVF incubation of the collected eggs contributes to the improvement of the quality of eggs; therefore, it may increase subsequent pregnancy and implantation rates following embryo transfer.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/rmb2.12652","type":"journal-article","created":{"date-parts":[[2025,5,3]],"date-time":"2025-05-03T02:49:12Z","timestamp":1746240552000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["The quality of human eggs and its pre\u2010\n                    <scp>IVF<\/scp>\n                    incubation"],"prefix":"10.1002","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9938-1354","authenticated-orcid":false,"given":"Ri\u2010Cheng","family":"Chian","sequence":"first","affiliation":[{"name":"Laboratory of Research and Development ARSCI Biomedical Inc.  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