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The endometritis recurred following a standard antibiotic regimen.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Outcome<\/jats:title>\n                    <jats:p>\n                      Microbiome analysis via 16S rRNA gene sequencing revealed persistent dysbiosis in both vaginal and endometrial samples despite antibiotic regimens. Whole\u2010exome sequencing (WES) identified rare variants in\n                      <jats:italic>TRPV3<\/jats:italic>\n                      and\n                      <jats:italic>CD36<\/jats:italic>\n                      , potentially associated with epithelial barrier dysfunction. Following an extended course of antibiotic therapy, the woman gave birth to a healthy baby at GA 32\u2009weeks.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This case highlights the possibility that barrier gene variants may be associated with persistent endometrial dysbiosis and recurrence of CE. An intensive antibiotic regimen may help achieve a viable pregnancy in patients with recurrent CE following standard antibiotic therapy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/rmb2.70098","type":"journal-article","created":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T07:32:14Z","timestamp":1789198334000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Successful Live Birth Following Treatment of Persistent Endometrial Dysbiosis and Recurrent Chronic Endometritis: A Case Report"],"prefix":"10.1002","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0726-1030","authenticated-orcid":false,"given":"Pao\u2010Lin","family":"Kuo","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Jen\u2010Ai Hospital  Taichung Taiwan"},{"name":"Department of Obstetrics and Gynecology National Cheng Kung University Hospital, National Cheng Kung University  Tainan 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