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ZIKV was little known during the initial outbreaks in Yap islands and French Polynesia, but it came to attention after the series of Brazil outbreaks in which severe complications like microcephaly in newborn babies was detected. During 2018, outbreaks of ZIKV occurred in two states of India which, being a tropical country, has congenial climatic conditions, abundance of highly competent mosquito vectors such as <jats:italic>Aedes aegypti<\/jats:italic> and <jats:italic>Aedes albopictus<\/jats:italic>, and an immunologically na\u00efve population. In this review, we will briefly discuss the history, epidemiology, evolution, transmission (vector\u2010borne and non\u2010vector borne), pathogenesis, clinical signs and unusual presentations, laboratory diagnosis, treatment, prevention and control of ZIKV. Finally, we suggest priorities for urgent research required to address unanswered questions about Zika infections and help bring this virus under control.<\/jats:p>","DOI":"10.1002\/rmv.2145","type":"journal-article","created":{"date-parts":[[2020,7,31]],"date-time":"2020-07-31T05:35:41Z","timestamp":1596173741000},"page":"1-9","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["The expanding arms of Zika virus: An updated review with recent Indian outbreaks"],"prefix":"10.1002","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7356-4507","authenticated-orcid":false,"given":"Ankita","family":"Agarwal","sequence":"first","affiliation":[{"name":"State Virology Laboratory, Department of Microbiology Gandhi Medical College  Bhopal India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deepti","family":"Chaurasia","sequence":"additional","affiliation":[{"name":"State Virology Laboratory, Department of Microbiology Gandhi Medical College  Bhopal India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,7,30]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(52)90042-4"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(54)90006-1"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1969.18.411"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(81)90100-0"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0805715"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0002681"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid2006.140138"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/1469-0691.12707"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES2014.19.9.20720"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES2014.19.13.20751"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2015.04.021"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid2110.150847"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1590\/0074-02760150192"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid2110.151125"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2016.03.010"},{"key":"e_1_2_13_17_1","unstructured":"European Centre for Disease Prevention and Control.Epidemiological update;2016.https:\/\/ecdc.europa.eu\/en\/news-events\/epidemiological-update-outbreaks-zika-virus-and-complications-potentially-linked-zika-1. 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