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The mean (confidence interval [CI]) of age and gestational age of admission (GA) in pregnant women was 33 (28\u201337) years old and 36 (34\u201337) weeks, respectively. Pregnant women show the same manifestations of COVID\u201019 as non\u2010pregnant adult patients. Fever (pregnant: 75.5%; non\u2010pregnant: 74%) and cough (pregnant: 48.5%; non\u2010pregnant: 53.5%) are the most common symptoms in both groups followed by myalgia (26.5%) and chill (25%) in pregnant and dysgeusia (27%) and fatigue (26.5%) in non\u2010pregnant patients. Pregnant women are less probable to show cough (odds ratio [OR] 0.7; 95% CI 0.67\u20130.75), fatigue (OR: 0.58; CI: 0.54\u20130.61), sore throat (OR: 0.66; CI: 0.61\u20130.7), headache (OR: 0.55; CI: 0.55\u20130.58) and diarrhea (OR: 0.46; CI: 0.4\u20130.51) than non\u2010pregnant adult patients. The most common imaging found in pregnant women is ground\u2010glass opacity (57%) and in non\u2010pregnant patients is consolidation (76%). Pregnant women have higher proportion of leukocytosis (27% vs. 14%), thrombocytopenia (18% vs. 12.5%) and have lower proportion of raised C\u2010reactive protein (52% vs. 81%) compared with non\u2010pregnant patients. Leucopenia and lymphopenia are almost the same in both groups. The most common comorbidity in pregnant patients is diabetes (18%) and in non\u2010pregnant patients is hypertension (21%). Case fatality rate (CFR) of non\u2010pregnant hospitalized patients is 6.4% (4.4\u20138.5), and mortality due to all\u2010cause for pregnant patients is 11.3% (9.6\u201313.3). Regarding the complications of pregnancy, postpartum hemorrhage (54.5% [7\u201394]), caesarean delivery (48% [42\u201354]), preterm labor (25% [4\u201374]) and preterm birth (21% [12\u201334]) are in turn the most prevalent complications. Comparing the pregnancy outcomes show that caesarean delivery (OR: 3; CI: 2\u20135), low birth weight (LBW) (OR: 9; CI: 2.4\u201330) and preterm birth (OR: 2.5; CI: 1.5\u20133.5) are more probable in pregnant woman with COVID\u201019 than pregnant women without COVID\u201019. The most prevalent neonatal complications are neonatal intensive care unit admission (43% [2\u201396]), fetal distress (30% [12\u201358]) and LBW (25% [16\u201337]). The rate of vertical transmission is 5.3% (1.3\u201316), and the rate of positive SARS\u2010CoV\u20102 test for neonates born to mothers with COVID\u201019 is 8% (4\u201316). Overall, pregnant patients present with the similar clinical characteristics of COVID\u201019 when compared with the general population, but they may be more asymptomatic. Higher odds of caesarean delivery, LBW and preterm birth among pregnant patients with COVID\u201019 suggest a possible association between COVID\u201019 infection and pregnancy complications. Low risk of vertical transmission is present, and SARS\u2010CoV\u20102 can be detected in all conception products, particularly placenta and breast milk. Interpretations of these results should be done cautiously due to the heterogeneity between studies; however, we believe our findings can guide the prenatal and postnatal considerations for COVID\u201019 pregnant patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/rmv.2208","type":"journal-article","created":{"date-parts":[[2021,1,2]],"date-time":"2021-01-02T13:12:10Z","timestamp":1609593130000},"page":"1-16","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":227,"title":["Clinical characteristics and outcomes of pregnant women with COVID\u201019 and comparison with control patients: A systematic review and meta\u2010analysis"],"prefix":"10.1002","volume":"31","author":[{"given":"Maryamsadat","family":"Jafari","sequence":"first","affiliation":[{"name":"Department of Obstetrics, Gynecology, and Perinatology Hamedan University of Medical Science  Hamedan Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Pormohammad","sequence":"additional","affiliation":[{"name":"Department of Biological Sciences University of Calgary  Calgary Alberta Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saeideh Aghayari","family":"Sheikh Neshin","sequence":"additional","affiliation":[{"name":"Neuroscience Research Center Guilan University of Medical Sciences  Rasht Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9284-6983","authenticated-orcid":false,"given":"Saied","family":"Ghorbani","sequence":"additional","affiliation":[{"name":"Department of Virology Faculty of Medicine Iran University of Medical Science  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4164-6556","authenticated-orcid":false,"given":"Deepanwita","family":"Bose","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Division of Infectious Diseases Boston Children's Hospital  Boston Massachusetts USA"},{"name":"Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shohreh","family":"Alimohammadi","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Gynecology, and Perinatology Hamedan University of Medical Science  Hamedan Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sedigheh","family":"Basirjafari","sequence":"additional","affiliation":[{"name":"Department of Radiology Hashemi Rafsanjani Hospital North Khorasan University of Medical Sciences  Shirvan Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehdi","family":"Mohammadi","sequence":"additional","affiliation":[{"name":"Department of Biological Science University of Calgary  Calgary Alberta Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cody","family":"Rasmussen\u2010Ivey","sequence":"additional","affiliation":[{"name":"John B. 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