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The PubMed, Web of Science, and Scopus databases were searched up to 1 December 2020. Overall, pooled prevalence and odds ratio of antibodies against HAdV\u201036 in people with obesity and controls was assessed among different ages. Case\u2010control and cohort studies were included in the analysis. The overall prevalence of HAdV\u201036 infection in obese population was 31% (CI: 0.24%\u20130.38%) which was 32% in cases and 27% in controls, respectively; a significant association was found between the cases and the controls (OR, 1.84; 95% CI, 1.39\u20132.43), especially in children younger than 18\u00a0years of age (OR, 2.44; 95% CI, 1.85\u20133.22). 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