{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:08:04Z","timestamp":1787166484259,"version":"build-2736575974"},"reference-count":74,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,3,3]],"date-time":"2022-03-03T00:00:00Z","timestamp":1646265600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Reviews in Medical Virology"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>SARS\u2010CoV\u20102 and dengue virus co\u2010infection cases have been on the rise in dengue\u2010endemic regions as coronavirus disease 2019 (COVID\u201019) spreads over the world, posing a threat of a co\u2010epidemic. The risk of comorbidity in co\u2010infection cases is greater than that of a single viral infection, which is a cause of concern. Although the pathophysiologies of the two infections are different, the viruses have comparable effects within the body, resulting in identical clinical symptoms in the case of co\u2010infection, which adds to the complexity. Overlapping symptoms and laboratory features make proper differentiation of the infections important. However, specific biomarkers provide precise results that can be utilised to diagnose and treat a co\u2010infection, whether it is simply COVID\u201019, dengue, or a co\u2010infection. Though their treatment is distinguished, it becomes more complicated in circumstances of co\u2010infection. As a result, regardless of whatever infection the first symptom points to, confirmation diagnosis of both COVID\u201019 and dengue should be mandatory, particularly in dengue\u2010endemic regions, to prevent health deterioration in individuals treated for a single infection. There is still a scarcity of concise literature on the epidemiology, pathophysiology, diagnosis, therapy, and management of SARS\u2010CoV\u20102 and dengue virus co\u2010infection. The epidemiology of SARS\u2010CoV\u20102 and dengue virus co\u2010infection, the mechanism of pathogenesis, and the potential impact on patients are summarised in this review. The possible diagnosis with biomarkers, treatment, and management of the SARS\u2010CoV\u20102 and dengue viruses are also discussed. This review will shed light on the appropriate diagnosis, treatment, and management of the patients suffering from SARS\u2010CoV\u20102 and dengue virus co\u2010infection.<\/jats:p>","DOI":"10.1002\/rmv.2340","type":"journal-article","created":{"date-parts":[[2022,3,3]],"date-time":"2022-03-03T07:28:23Z","timestamp":1646292503000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":55,"title":["SARS\u2010CoV\u20102 and dengue virus co\u2010infection: Epidemiology, pathogenesis, diagnosis, treatment, and management"],"prefix":"10.1002","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6899-0085","authenticated-orcid":false,"given":"Chowdhury Nusaiba Binte Sayed","family":"Prapty","sequence":"first","affiliation":[{"name":"Department of Immunology School of Basic Medical Sciences Fujian Medical University  Fuzhou China"},{"name":"Biotechnology Program, Department of Mathematics and Natural Sciences BRAC University  Dhaka Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7312-0845","authenticated-orcid":false,"given":"Raad","family":"Rahmat","sequence":"additional","affiliation":[{"name":"Department of Immunology School of Basic Medical Sciences Fujian Medical University  Fuzhou China"},{"name":"Biotechnology Program, Department of Mathematics and Natural Sciences BRAC University  Dhaka Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0144-5875","authenticated-orcid":false,"given":"Yusha","family":"Araf","sequence":"additional","affiliation":[{"name":"Department of Immunology School of Basic Medical Sciences Fujian Medical University  Fuzhou China"},{"name":"Department of Genetic Engineering and Biotechnology School of Life Sciences Shahjalal University of Science and Technology  Sylhet Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2270-1978","authenticated-orcid":false,"given":"Samiha Kamal","family":"Shounak","sequence":"additional","affiliation":[{"name":"Biotechnology Program, Department of Mathematics and Natural Sciences BRAC University  Dhaka Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0041-8533","authenticated-orcid":false,"family":"Noor\u2010A\u2010Afrin","sequence":"additional","affiliation":[{"name":"Biotechnology Program, Department of Mathematics and Natural Sciences BRAC University  Dhaka Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5225-5767","authenticated-orcid":false,"given":"Tanjim Ishraq","family":"Rahaman","sequence":"additional","affiliation":[{"name":"Department of Biotechnology and Genetic Engineering Faculty of Life Sciences Bangabandhu Sheikh Mujibur Rahman Science and Technology University  Gopalganj Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6444-0214","authenticated-orcid":false,"given":"Mohammad Jakir","family":"Hosen","sequence":"additional","affiliation":[{"name":"Department of Genetic Engineering and Biotechnology School of Life Sciences Shahjalal University of Science and Technology  Sylhet Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8797-1322","authenticated-orcid":false,"given":"Chunfu","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Immunology School of Basic Medical Sciences Fujian Medical University  Fuzhou China"},{"name":"Department of Microbiology, Immunology and Infectious Diseases University of Calgary  Calgary Alberta Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1487-5444","authenticated-orcid":false,"given":"Md. 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