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However, the relationship between testosterone (T) and Covid\u201019 remains unclear with both protective and deleterious effects on different aspects of the disease suggested. Here, we review the current epidemiological and biological evidence on the role of testosterone in the process of SARS\u2010CoV\u20102 infection and in mediating Covid\u201019 severity, its potential to serve as a biomarker for risk stratification and discuss the possibility of T supplementation as a treatment or preventative therapy for Covid\u201019.<\/jats:p>","DOI":"10.1002\/rmv.2395","type":"journal-article","created":{"date-parts":[[2022,9,3]],"date-time":"2022-09-03T09:44:43Z","timestamp":1662198283000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Testosterone and Covid\u201019: An update"],"prefix":"10.1002","volume":"33","author":[{"given":"Aksam","family":"Yassin","sequence":"first","affiliation":[{"name":"Surgical Research Section Hamad Medical Corporation  Doha Qatar"},{"name":"Center of Medicine and Health Sciences Dresden International University  Dresden 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