{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T11:41:38Z","timestamp":1783942898827,"version":"3.55.0"},"reference-count":113,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,3,30]],"date-time":"2023-03-30T00:00:00Z","timestamp":1680134400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Reviews in Medical Virology"],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Mpox (previously known as monkeypox) continues to raise concerns since many cases are still being recorded globally. Various reports have shown changing epidemiology of the disease, together with different atypical clinical characteristics of affected patients. The condition has reportedly been self\u2010limited since most patients do not usually require hospitalisation. However, recent reports showed that some patients might suffer from related complications and require hospitalisation. Different systems were reportedly affected, including cardiac, neurological, respiratory, and renal events. In the present literature review, we aim to review these complications, discuss their potential mechanisms, and provide insight into the currently recommended diagnostic and management practices.<\/jats:p>","DOI":"10.1002\/rmv.2443","type":"journal-article","created":{"date-parts":[[2023,3,31]],"date-time":"2023-03-31T05:50:35Z","timestamp":1680241835000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Mpox impact on different organ systems: Complications, mechanisms, and management"],"prefix":"10.1002","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2180-0029","authenticated-orcid":false,"given":"Abdullah","family":"Reda","sequence":"first","affiliation":[{"name":"Faculty of Medicine Al\u2010Azhar University  Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7469-4752","authenticated-orcid":false,"given":"Kuldeep","family":"Dhama","sequence":"additional","affiliation":[{"name":"Division of Pathology ICAR\u2010Indian Veterinary Research Institute (IVRI)  Bareilly Uttar Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,3,30]]},"reference":[{"key":"e_1_2_16_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cit703"},{"key":"e_1_2_16_3_1","doi-asserted-by":"publisher","DOI":"10.1128\/br.37.1.1\u201018.1973"},{"key":"e_1_2_16_4_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.add1583"},{"issue":"5","key":"e_1_2_16_5_1","first-page":"593","article-title":"A human infection caused by monkeypox virus in Basankusu Territory, Democratic Republic of the Congo","volume":"46","author":"Ladnyj ID","year":"1972","journal-title":"Bull World Health Organ"},{"key":"e_1_2_16_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cytogfr.2022.10.002"},{"issue":"27","key":"e_1_2_16_7_1","first-page":"642","article-title":"Update: multistate outbreak of monkeypox\u2010\u2010Illinois, Indiana, Kansas, Missouri, Ohio, and Wisconsin, 2003","volume":"52","year":"2003","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"e_1_2_16_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amsu.2022.104417"},{"key":"e_1_2_16_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/156.2.293"},{"key":"e_1_2_16_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tmaid.2022.102456"},{"key":"e_1_2_16_11_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7132e3"},{"key":"e_1_2_16_12_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7144e1"},{"key":"e_1_2_16_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12941\u2010022\u201000527\u20101"},{"key":"e_1_2_16_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s15010\u2010022\u201001937\u20101"},{"key":"e_1_2_16_15_1","doi-asserted-by":"publisher","DOI":"10.2807\/1560\u20107917.Es.2022.27.27.2200471"},{"key":"e_1_2_16_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40249\u2010022\u201001007\u20106"},{"key":"e_1_2_16_17_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.add5966"},{"key":"e_1_2_16_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/s1473\u20103099(22)00411\u2010x"},{"key":"e_1_2_16_19_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7135e1"},{"key":"e_1_2_16_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10461\u2010021\u201003180\u20105"},{"key":"e_1_2_16_21_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879\u2010019\u20104559\u20101"},{"key":"e_1_2_16_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/qad.0000000000002111"},{"key":"e_1_2_16_23_1","doi-asserted-by":"publisher","DOI":"10.1590\/0037\u20108682\u20100392\u20102022"},{"key":"e_1_2_16_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(23)00273\u20108"},{"key":"e_1_2_16_25_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2220415120"},{"key":"e_1_2_16_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tmaid.2022.102402"},{"key":"e_1_2_16_27_1","doi-asserted-by":"publisher","DOI":"10.1177\/20499361221124027"},{"key":"e_1_2_16_28_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0010141"},{"key":"e_1_2_16_29_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciaa143"},{"key":"e_1_2_16_30_1","doi-asserted-by":"publisher","DOI":"10.1086\/425039"},{"key":"e_1_2_16_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.26473"},{"key":"e_1_2_16_32_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7138e1"},{"key":"e_1_2_16_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473\u20103099(22)00741\u20101"},{"key":"e_1_2_16_34_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3182840b95"},{"key":"e_1_2_16_35_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.294.21.2744"},{"key":"e_1_2_16_36_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.5380.434\u2010b"},{"key":"e_1_2_16_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/s1473\u20103099(22)00228\u20106"},{"key":"e_1_2_16_38_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2022.3491"},{"key":"e_1_2_16_39_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2021.634827"},{"key":"e_1_2_16_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tmaid.2022.102414"},{"key":"e_1_2_16_41_1","doi-asserted-by":"publisher","DOI":"10.1038\/d41586\u2010022\u201002931\u20101"},{"key":"e_1_2_16_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474\u20104422(22)00340\u20104"},{"key":"e_1_2_16_43_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2207323"},{"key":"e_1_2_16_44_1","doi-asserted-by":"publisher","DOI":"10.5005\/jp\u2010journals\u201010071\u201023187"},{"key":"e_1_2_16_45_1","doi-asserted-by":"publisher","DOI":"10.1212\/wnl.37.2.179"},{"key":"e_1_2_16_46_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2020201697"},{"key":"e_1_2_16_47_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciac622"},{"key":"e_1_2_16_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473\u20103099(23)00044\u20100"},{"key":"e_1_2_16_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473\u20103099(23)00054\u20103"},{"key":"e_1_2_16_50_1","doi-asserted-by":"publisher","DOI":"10.3390\/v9110320"},{"key":"e_1_2_16_51_1","doi-asserted-by":"publisher","DOI":"10.1080\/14787210.2020.1819791"},{"key":"e_1_2_16_52_1","doi-asserted-by":"publisher","DOI":"10.1128\/aac.01226\u201022"},{"key":"e_1_2_16_53_1","doi-asserted-by":"publisher","DOI":"10.1128\/aac.00762\u201007"},{"key":"e_1_2_16_54_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro1099"},{"key":"e_1_2_16_55_1","doi-asserted-by":"publisher","DOI":"10.1177\/0300985810378649"},{"key":"e_1_2_16_56_1","doi-asserted-by":"publisher","DOI":"10.1038\/labinvest.3780373"},{"key":"e_1_2_16_57_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1000249"},{"key":"e_1_2_16_58_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003\u20104819\u2010126\u20104\u2010199702150\u201000001"},{"key":"e_1_2_16_59_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7137e1"},{"key":"e_1_2_16_60_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2022.15336"},{"key":"e_1_2_16_61_1","doi-asserted-by":"publisher","DOI":"10.1159\/000528041"},{"key":"e_1_2_16_62_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2020.19209"},{"key":"e_1_2_16_63_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7122e1"},{"key":"e_1_2_16_64_1","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofac310"},{"key":"e_1_2_16_65_1","doi-asserted-by":"publisher","DOI":"10.1111\/tme.12918"},{"key":"e_1_2_16_66_1","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofac394"},{"key":"e_1_2_16_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaccas.2022.08.033"},{"key":"e_1_2_16_68_1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.29638"},{"key":"e_1_2_16_69_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2008.05.044"},{"key":"e_1_2_16_70_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0118283"},{"key":"e_1_2_16_71_1","doi-asserted-by":"publisher","DOI":"10.1086\/524747"},{"key":"e_1_2_16_72_1","doi-asserted-by":"publisher","DOI":"10.1159\/000165631"},{"key":"e_1_2_16_73_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.49.3.333"},{"key":"e_1_2_16_74_1","doi-asserted-by":"publisher","DOI":"10.1086\/651453"},{"key":"e_1_2_16_75_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/eht210"},{"key":"e_1_2_16_76_1","doi-asserted-by":"publisher","DOI":"10.1177\/2048872620910109"},{"key":"e_1_2_16_77_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2019.08.027"},{"key":"e_1_2_16_78_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid2812.221276"},{"key":"e_1_2_16_79_1","doi-asserted-by":"publisher","DOI":"10.3390\/v13081571"},{"key":"e_1_2_16_80_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0055488"},{"key":"e_1_2_16_81_1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.26531"},{"key":"e_1_2_16_82_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid2604.191164"},{"key":"e_1_2_16_83_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00455\u2010022\u201010481\u2010x"},{"key":"e_1_2_16_84_1","doi-asserted-by":"publisher","DOI":"10.1089\/lap.2022.0473"},{"key":"e_1_2_16_85_1","article-title":"Another epidemic in the shadow of covid 19 pandemic: a review of monkeypox","volume":"7","author":"Okyay RA","year":"2022","journal-title":"Proteins"},{"key":"e_1_2_16_86_1","doi-asserted-by":"publisher","DOI":"10.1177\/09564624221114998"},{"key":"e_1_2_16_87_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2022.08.014"},{"key":"e_1_2_16_88_1","doi-asserted-by":"publisher","DOI":"10.3390\/tropicalmed7100318"},{"key":"e_1_2_16_89_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.1094346"},{"key":"e_1_2_16_90_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj\u20102022\u2010072410"},{"key":"e_1_2_16_91_1","doi-asserted-by":"publisher","DOI":"10.3238\/arztebl.2020.0500"},{"key":"e_1_2_16_92_1","doi-asserted-by":"publisher","DOI":"10.5001\/omj.2022.52"},{"key":"e_1_2_16_93_1","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.120.314515"},{"key":"e_1_2_16_94_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2021211396"},{"key":"e_1_2_16_95_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2021.22070"},{"key":"e_1_2_16_96_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00200210"},{"key":"e_1_2_16_97_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440\u20101843.2009.01534.x"},{"key":"e_1_2_16_98_1","doi-asserted-by":"publisher","DOI":"10.1074\/mcp.M110.001875"},{"key":"e_1_2_16_99_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.icb.7100033"},{"key":"e_1_2_16_100_1","doi-asserted-by":"publisher","DOI":"10.3390\/v9120380"},{"key":"e_1_2_16_101_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tmaid.2022.102459"},{"key":"e_1_2_16_102_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41577\u2010022\u201000775\u20104"},{"key":"e_1_2_16_103_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0077804"},{"key":"e_1_2_16_104_1","doi-asserted-by":"publisher","DOI":"10.1101\/2022.05.26.22273379"},{"key":"e_1_2_16_105_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473\u20103099(22)00806\u20104"},{"key":"e_1_2_16_106_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jiph.2023.01.006"},{"key":"e_1_2_16_107_1","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.02012\u201009"},{"key":"e_1_2_16_108_1","doi-asserted-by":"publisher","DOI":"10.1128\/mSphere.00927\u201020"},{"key":"e_1_2_16_109_1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.28230"},{"key":"e_1_2_16_110_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7132e4"},{"key":"e_1_2_16_111_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lanepe.2022.100536"},{"key":"e_1_2_16_112_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.27913"},{"key":"e_1_2_16_113_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2022.1023519"},{"key":"e_1_2_16_114_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2666\u20105247(22)00259\u20102"}],"container-title":["Reviews in Medical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rmv.2443","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,17]],"date-time":"2023-08-17T16:16:40Z","timestamp":1692289000000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/rmv.2443"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,30]]},"references-count":113,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,7]]}},"alternative-id":["10.1002\/rmv.2443"],"URL":"https:\/\/doi.org\/10.1002\/rmv.2443","archive":["Portico"],"relation":{},"ISSN":["1052-9276","1099-1654"],"issn-type":[{"value":"1052-9276","type":"print"},{"value":"1099-1654","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,3,30]]},"assertion":[{"value":"2022-12-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-03-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-03-30","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e2443"}}