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The widespread use of corticosteroids for the symptomatic treatment of COVID\u201019 could lead to the reactivation of infections of opportunistic pathogens, including\n                    <jats:italic>Strongyloides<\/jats:italic>\n                    . We sought to determine the clinical symptoms and demographic characteristics of SARS\u2010CoV\u20102\u2013\n                    <jats:italic>Strongyloides<\/jats:italic>\n                    co\u2010infection, particularly in patients with severe disease and being treated with immunosuppressive drugs. To do this, we undertook a systematic review of the literature, and searched public accessible scientific databases\u2014the Web of Science, Scopus, PubMed\/Medline and Embase \u2013for eligible studies (1 December 2019 to 30 August 2022). The review protocol is registered in PROSPERO (CRD42022377062). Descriptive statistical analyses were used to present the clinical and laboratory parameters of the co\u2010infection; for this, we calculated prevalence using the following formula: positive cases\/total number of cases\u00a0\u00d7\u00a0100. Of a total of 593 studies identified, 17 studies reporting 26 co\u2010infected patients met the criteria for inclusion in this review. The median age of these patients was 55.14\u00a0years. Most of cases (53.8%) were treated with dexamethasone, followed by methylprednisolone (26.9%). Eighteen of 26 patients were immigrants living in European countries or the USA; most of these immigrants originated from Latin America (58%) and South\u2010East Asia (11%). The commonest symptoms of co\u2010infection were abdominal pain (50%), fever (46.1%), dyspnoea (30.7%) and cough (30.7%), and frequently reported laboratory findings were high absolute eosinophil count (38.4%), high white blood cell count (30.7%), high C\u2010reactive protein (23.0%) and high neutrophil count (19.2%). Two of the 26 patients (7.7%) had fatal outcomes. Most of the SARS\u2010CoV\u20102\u2013\n                    <jats:italic>Strongyloides<\/jats:italic>\n                    coinfected cases were immigrants living in developed countries, emphasising the need for clinicians in these countries to be aware of clinical and laboratory parameters associated with such co\u2010infections, as well as the key importance of rapid and accurate diagnostic tests for timely and effective diagnosis and patient management.\n                  <\/jats:p>","DOI":"10.1002\/rmv.2469","type":"journal-article","created":{"date-parts":[[2023,6,24]],"date-time":"2023-06-24T21:15:10Z","timestamp":1687641310000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["<i>Strongyloides<\/i>\n                    coinfection in COVID\u201019 patients treated with corticosteroids: A systematic review"],"prefix":"10.1002","volume":"33","author":[{"given":"Sana","family":"Zulfiqar","sequence":"first","affiliation":[{"name":"School of Medicine Trinity College Dublin The University of Dublin  Dublin 2 Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robin B.","family":"Gasser","sequence":"additional","affiliation":[{"name":"Department of Veterinary Biosciences Melbourne Veterinary School Faculty of Science The University of Melbourne  Parkville Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sahar","family":"Ghodsian","sequence":"additional","affiliation":[{"name":"Department of Parasitology and Mycology School of Public Health Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mustafa","family":"Almukhtar","sequence":"additional","affiliation":[{"name":"Takhar Family Medicine and Urgent Care  Sacramento California United\u00a0States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Celia","family":"Holland","sequence":"additional","affiliation":[{"name":"Department of Zoology School of Natural Sciences, Trinity College Dublin, the University of Dublin, College Green Dublin  Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1358-1321","authenticated-orcid":false,"given":"Ali","family":"Rostami","sequence":"additional","affiliation":[{"name":"Infectious Diseases and Tropical Medicine Research Center Health Research Institute Babol University of Medical Sciences  Babol Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,6,23]]},"reference":[{"key":"e_1_2_11_2_1","unstructured":"World Health Organization.WHO Coronavirus (COVID\u201019) Dashboard. 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