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Hepatitis C virus (HCV) infection has a wide range of prevalence (2.6\u201366%) among renal transplant recipients living in different countries with great genotype diversity in different parts of the world. Nowadays, antiviral drugs are used for the management of hepatitis C. Because of graft\u2010threatening effects of some antiviral drugs used in HCV\u2010infected renal transplant recipients, we specifically focused on HCV treatment after renal transplantation. Treatment of post\u2010renal transplantation chronic liver disease with INF and ribavirin remains controversial. Anecdotal reports on post\u2010renal transplantation hepatitis C demonstrate encouraging findings. This review summarises the most current information on diagnosis, treatment, prognosis, complications as well as the new aspects of treatment in HCV\u2010infected renal transplant recipients. HCV belongs to the family of Flaviviridae, genus Hepacivirus. 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