{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T22:40:41Z","timestamp":1787956841546,"version":"build-2784847793"},"reference-count":52,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,11,8]],"date-time":"2024-11-08T00:00:00Z","timestamp":1731024000000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Reviews in Medical Virology"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Hepatitis B virus (HBV) Infection remains a public health problem and a threat to blood transfusion safety. The aim of this study was to summarise the scientific literature on the seroprevalence of HBV and occult HBV among blood donors in Africa. Searches were carried out in PubMed, Science Direct, Global Index Medicus and African Journals Online from 2012 to 2022. Dersimonian and Laird's random\u2010effects model\u2010based method was used for statistical analyses to estimate pooled seroprevalence at a 95% confidence interval (CI) using STATA version 14 software. Heterogeneity was assessed on the basis of Cochran's <jats:italic>Q<\/jats:italic> test and quantified by the <jats:italic>I<\/jats:italic><jats:sup>2<\/jats:sup> index. The methodological quality of the articles was assessed using the Joanna Brigg Institute's critical appraisal checklist. Among 90 articles included, 86 reported data in serological test that a pooled HBV seroprevalence of 5.53% (95% CI: 4.56\u20136.58; <jats:italic>I<\/jats:italic><jats:sup>2<\/jats:sup>\u00a0=\u00a099.94%) and 14 provided occult hepatitis B data. A high prevalence of 9.69% (95% CI: 8.42\u201311.03) was observed in the West African region. Lowest prevalence was 1.22% (95% CI: 0.74\u20131.83) in South Africa region. Prevalence in Africa among men was: 5.18% (95% CI: 3.97\u20136.54) and in women: 3.50% (95% CI: 2.45\u20134.71) (<jats:italic>I<\/jats:italic><jats:sup>2<\/jats:sup>\u00a0=\u00a099.76% and <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.01). While the overall pooled prevalence of occult hepatitis B was 3.18% (95% CI: 1.29\u20135.81). HBV seroprevalence is high in low\u2010resource areas of Africa, and the data generated by this situation calls for constant epidemiological surveillance. Emphasis must be placed on building blood donor loyalty and integrating molecular testing into the biological qualification of blood donations.<\/jats:p>","DOI":"10.1002\/rmv.70006","type":"journal-article","created":{"date-parts":[[2024,11,9]],"date-time":"2024-11-09T04:04:41Z","timestamp":1731125081000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Seroprevalence of Viral Hepatitis B and Occult Hepatitis B Among Blood Donors in Africa: A Systematic Review and Meta\u2010Analysis"],"prefix":"10.1002","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6294-7169","authenticated-orcid":false,"given":"Abibou","family":"Simpore","sequence":"first","affiliation":[{"name":"Medical Biology and Disease Surveillance Department (DBMSM) National Agency for Sanitary Safety of Environment, Alimentation, Work and Health Products (ANSSEAT)  Ouagadougou Burkina Faso"},{"name":"Laboratory of Molecular Biology and Genetics (LABIOGENE) Joseph KI\u2010ZERBO University  Ouagadougou Burkina Faso"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bapio Valerie E. J. T.","family":"Bazie","sequence":"additional","affiliation":[{"name":"Laboratory of Molecular Biology and Genetics (LABIOGENE) Joseph KI\u2010ZERBO University  Ouagadougou Burkina Faso"},{"name":"Department of Medical Biology Institute for Research in Health Science (IRSS)  Ouagadougou Burkina Faso"},{"name":"Molecular Biology Lab Biomolecular Research Center Pietro Annigoni (CERBA)  Ouagadougou Burkina Faso"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul A.","family":"Yooda","sequence":"additional","affiliation":[{"name":"National tuberculosis program National Reference Laboratory for Mycobacteria (LNR\u2010M)  Ouagadougou Burkina Faso"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdou Azaque","family":"Zoure","sequence":"additional","affiliation":[{"name":"Laboratory of Molecular Biology and Genetics (LABIOGENE) Joseph KI\u2010ZERBO University  Ouagadougou Burkina Faso"},{"name":"Department of Medical Biology Institute for Research in Health Science (IRSS)  Ouagadougou Burkina Faso"},{"name":"Molecular Biology Lab Biomolecular Research Center Pietro Annigoni (CERBA)  Ouagadougou Burkina Faso"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salam","family":"Sawadogo","sequence":"additional","affiliation":[{"name":"Ouagadougou Regional Blood Transfusion Center National Center for Blood Transfusion in Burkina Faso (CNTS)  Ouagadougou Burkina Faso"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdoul\u2010Guaniyi","family":"Sawadogo","sequence":"additional","affiliation":[{"name":"Ouagadougou Regional Blood Transfusion Center National Center for Blood Transfusion in Burkina Faso (CNTS)  Ouagadougou Burkina Faso"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dinanib\u00e9","family":"Kambir\u00e9","sequence":"additional","affiliation":[{"name":"Department of Medical Biology Institute for Research in Health Science (IRSS)  Ouagadougou Burkina Faso"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebeca T.","family":"Compaore","sequence":"additional","affiliation":[{"name":"Department of Medical Biology Institute for Research in Health Science (IRSS)  Ouagadougou Burkina Faso"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Issoufou","family":"Tao","sequence":"additional","affiliation":[{"name":"Laboratory of Molecular Biology and Genetics (LABIOGENE) Joseph KI\u2010ZERBO University  Ouagadougou Burkina Faso"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V\u00e9ronique S.","family":"Zongo","sequence":"additional","affiliation":[{"name":"Laboratory of Molecular Biology and Genetics (LABIOGENE) Joseph KI\u2010ZERBO University  Ouagadougou Burkina Faso"},{"name":"Molecular Biology Lab Biomolecular Research Center Pietro Annigoni (CERBA)  Ouagadougou Burkina Faso"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muller K. A.","family":"Compaore","sequence":"additional","affiliation":[{"name":"Medical Biology and Disease Surveillance Department (DBMSM) National Agency for Sanitary Safety of Environment, Alimentation, Work and Health Products (ANSSEAT)  Ouagadougou Burkina Faso"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrice A.","family":"Soubeiga","sequence":"additional","affiliation":[{"name":"Medical Biology and Disease Surveillance Department (DBMSM) National Agency for Sanitary Safety of Environment, Alimentation, Work and Health Products (ANSSEAT)  Ouagadougou Burkina Faso"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diderot","family":"Fopa","sequence":"additional","affiliation":[{"name":"Hematology &amp; Transfusion Service Yaounde University Teaching Hospital  Yaound\u00e9 Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cyrille","family":"Bisseye","sequence":"additional","affiliation":[{"name":"Laboratory of Molecular and Cellular Biology (LABMC) University of Science and Technology of Masuku (USTM)  Franceville Gabon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alice","family":"Kiba\u2010Koumare","sequence":"additional","affiliation":[{"name":"Ouagadougou Regional Blood Transfusion Center National Center for Blood Transfusion in Burkina Faso (CNTS)  Ouagadougou Burkina Faso"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florencia W.","family":"Djigma","sequence":"additional","affiliation":[{"name":"Laboratory of Molecular Biology and Genetics (LABIOGENE) Joseph KI\u2010ZERBO University  Ouagadougou Burkina Faso"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elie","family":"Kabre","sequence":"additional","affiliation":[{"name":"Medical Biology and Disease Surveillance Department (DBMSM) National Agency for Sanitary Safety of Environment, Alimentation, Work and Health Products (ANSSEAT)  Ouagadougou Burkina Faso"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacques","family":"Simpore","sequence":"additional","affiliation":[{"name":"Laboratory of Molecular Biology and Genetics (LABIOGENE) Joseph KI\u2010ZERBO University  Ouagadougou Burkina Faso"},{"name":"Molecular Biology Lab Biomolecular Research Center Pietro Annigoni (CERBA)  Ouagadougou Burkina Faso"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,11,8]]},"reference":[{"issue":"6","key":"e_1_2_11_2_1","first-page":"260","article-title":"Prevalence of Human Immunodeficiency Virus in Iranian Blood Donors: A Systematic Review and Meta\u2010Analysis","volume":"21","author":"Musavi H.","year":"2018","journal-title":"Archives of Iranian Medicine"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879\u2010021\u201006505\u2010w"},{"key":"e_1_2_11_4_1","volume-title":"D\u00e9pistage des infections transmissibles par transfusion dans les dons de sang: Recommandations","author":"OMS","year":"2010"},{"issue":"39","key":"e_1_2_11_5_1","first-page":"438","article-title":"Surveillance \u00e9pid\u00e9miologique des donneurs de sang et risque r\u00e9siduel de transmission du VIH, de l'HTLV, du VHC et du VHB par transfusion en France entre 2008 et","volume":"2012","author":"Pillonel J.","year":"2010","journal-title":"Bulletin \u00e9pid\u00e9miologique hebdomadaire"},{"issue":"1","key":"e_1_2_11_6_1","first-page":"16","article-title":"Post\u2010Transfusion Viral Hepatitis in Sickle Cell Anaemia: Retrospective\u2010Prospective Analysis","volume":"5","author":"Fasola F.","year":"2002","journal-title":"Nigerian Journal of Clinical Practice"},{"key":"e_1_2_11_7_1","volume-title":"Report on the Global HIV\/AIDS Epidemic 2008","author":"UNAIDS","year":"2008"},{"key":"e_1_2_11_8_1","volume-title":"H\u00e9patite B: Principaux rep\u00e8res","author":"OMS","year":"2024"},{"key":"e_1_2_11_9_1","first-page":"315","volume-title":"Relev\u00e9 \u00e9pid\u00e9miologique hebdomadaire","author":"OMS","year":"2023"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0042\u20109007.2004.00406.x"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2019.03.034"},{"key":"e_1_2_11_12_1","volume-title":"Guidelines for the Prevention, Care and Treatment of Persons With Chronic Hepatitis B Infection","author":"WHO","year":"2015"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(90)91874-A"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0272920"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.4166\/kjg.2013.62.3.160"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1159\/000457965"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0168\u20108278(96)80232\u20107"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl\u20102018\u2010316490"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.3390\/v14112507"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n71"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.15171\/ijhpm.2014.71"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1186\/2049\u20103258\u201072\u201039"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/0197\u20102456(86)90046\u20102"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.1186"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.d4002"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.315.7109.629"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1423\u20100410.2012.01640.x"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.4103\/npmj.npmj_19_22"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.25248"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0131912"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.16559"},{"key":"e_1_2_11_32_1","unstructured":"WHO Global Hepatitis Report 2017 (2017) https:\/\/iris.who.int\/bitstream\/handle\/10665\/255016\/9789241565455\u2010eng.pdf?sequence=1."},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tracli.2021.01.007"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tracli.2013.10.002"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537\u20102995.2011.03355.x"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.34172\/mejdd.2021.231"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0079203"},{"key":"e_1_2_11_38_1","volume-title":"Fiche de synth\u00e8se analytique: L\u2019\u00e9limination de l\u2019h\u00e9patite ne peut plus attendre","author":"OMS","year":"2023"},{"key":"e_1_2_11_39_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/781843"},{"key":"e_1_2_11_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcvp.2022.100122"},{"key":"e_1_2_11_41_1","doi-asserted-by":"publisher","DOI":"10.4314\/ijbcs.v16i1.2"},{"key":"e_1_2_11_42_1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.47066"},{"key":"e_1_2_11_43_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879\u2010023\u201008110\u20105"},{"key":"e_1_2_11_44_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365\u20102893.1997.00052.x"},{"key":"e_1_2_11_45_1","doi-asserted-by":"publisher","DOI":"10.4314\/ejhs.v26i2.9"},{"key":"e_1_2_11_46_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10900\u2010020\u201000862\u20104"},{"key":"e_1_2_11_47_1","doi-asserted-by":"publisher","DOI":"10.11604\/pamj.2018.31.81.16331"},{"key":"e_1_2_11_48_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12889\u2010018\u20105555\u2010x"},{"key":"e_1_2_11_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tracli.2021.05.011"},{"key":"e_1_2_11_50_1","doi-asserted-by":"publisher","DOI":"10.1186\/s42506\u2010023\u201000138\u20104"},{"key":"e_1_2_11_51_1","doi-asserted-by":"publisher","DOI":"10.1002\/jgh3.12411"},{"key":"e_1_2_11_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/s1246\u20107820(96)80008\u20105"},{"key":"e_1_2_11_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tracli.2006.03.015"}],"container-title":["Reviews in Medical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rmv.70006","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,11]],"date-time":"2025-04-11T18:29:42Z","timestamp":1744396182000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/rmv.70006"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11]]},"references-count":52,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,11]]}},"alternative-id":["10.1002\/rmv.70006"],"URL":"https:\/\/doi.org\/10.1002\/rmv.70006","archive":["Portico"],"relation":{},"ISSN":["1052-9276","1099-1654"],"issn-type":[{"value":"1052-9276","type":"print"},{"value":"1099-1654","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11]]},"assertion":[{"value":"2024-05-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-22","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-11-08","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70006"}}