{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T04:46:19Z","timestamp":1764305179667,"version":"3.46.0"},"reference-count":45,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T00:00:00Z","timestamp":1762041600000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Reviews in Medical Virology"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Vaccination is an effective response to the COVID\u201019 pandemic, but vaccine hesitancy is a major challenge. This study aims to explore the pooled prevalence and factors of COVID\u201019 vaccine hesitancy. We searched the studies published from January 2020 to December 2023 in PubMed, Web of Science, and Embase. The studies with complete start time of the study and national information were included in the generalised additive model to explore the factors affecting the COVID\u201019 vaccine hesitancy rate by calculating OR and 95%CI. A total of 629 studies were included. The pooled global hesitancy rates of COVID\u201019 vaccine were 34.6% (95% CI: 31.2%\u201338.1%) in vulnerable population and 33.2% (95% CI: 31.7%\u201334.8%) in general populations. The regression model showed that the hesitancy rate of COVID\u201019 vaccine was correlated with the duration of the epidemic, the monthly governmental stringency index, the monthly incidence and mortality of COVID\u201019, SDI, geographical location, and health status. Local governments should pay special attention to vaccination of vulnerable population and encourage vaccination to cope with the next possible wave of pandemic as incidence declines and restrictions are eased. The international community should timely provide vaccines for low economy countries.<\/jats:p>","DOI":"10.1002\/rmv.70079","type":"journal-article","created":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T05:10:26Z","timestamp":1762146626000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Global Hesitancy of COVID\u201019 Vaccine Among Vulnerable Population From 2020 to 2023: A Systematic Review and Meta\u2010Analysis"],"prefix":"10.1002","volume":"35","author":[{"given":"Qingsong","family":"Xu","sequence":"first","affiliation":[{"name":"Department of Epidemiology and Biostatistics School of Public Health Peking University  Beijing China"},{"name":"Department of Laboratorial Science and Technology &amp; Vaccine Research Center School of Public Health Peking University  Beijing China"},{"name":"Center for Infectious Diseases and Policy Research &amp; Global Health and Infectious Diseases Group Peking 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