{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T19:51:04Z","timestamp":1792612264921,"version":"4.5.0"},"reference-count":79,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,2,23]],"date-time":"2026-02-23T00:00:00Z","timestamp":1771804800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,2,23]],"date-time":"2026-02-23T00:00:00Z","timestamp":1771804800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Reviews in Medical Virology"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Oncogenic viruses, including Epstein\u2010Barr virus (EBV), Human Papillomavirus (HPV), Kaposi's Sarcoma\u2010Associated Herpesvirus (KSHV), Hepatitis B Virus (HBV), Merkel Cell Polyomavirus (MCPyV), Human T\u2010cell Lymphotropic Virus (HTLV\u20101), and Hepatitis C Virus (HCV), are significant contributors to cancer development, each through distinct mechanisms. EBV is recognised for its association with cancers such as Burkitt lymphoma and nasopharyngeal carcinoma. High\u2010risk types of HPV are primarily connected to cervical cancer. KSHV plays a crucial role in the development of Kaposi's sarcoma, especially among individuals with compromised immune systems. Both HBV and HCV are implicated in liver cancer due to chronic infections and resultant inflammation. MCPyV is linked to aggressive skin cancers, while HTLV\u20101 can lead to leukemia and various neurological complications. Collectively, these viruses account for approximately 20% of all cancers globally, providing valuable insights into cancer pathogenesis and potential treatment avenues. Effective management of these viruses includes the use of vaccines such as Gardasil for HPV and antiviral medications for HBV and HCV. Treatment options for cancers associated with EBV, KSHV, and MCPyV encompass targeted therapies and surgical interventions. Preventive measures emphasise vaccination, safe practices to curb virus transmission, routine screenings, and maintaining a healthy lifestyle. Ongoing research and public health initiatives are vital for enhancing prevention and treatment strategies, particularly in high\u2010risk and resource\u2010limited settings. By deepening our understanding of these viruses, we can improve the development of targeted therapies and strive to reduce the global burden of cancer.<\/jats:p>","DOI":"10.1002\/rmv.70121","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T23:32:09Z","timestamp":1773012729000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["A Deep Dive Into Oncogenic Viruses Understanding Their Role in Cancer and Approaches for Prevention"],"prefix":"10.1002","volume":"36","author":[{"given":"Neetesh","family":"Jindal","sequence":"first","affiliation":[{"name":"Department of Virology ICMR\u2010Rajendra Memorial Research Institute of Medical Sciences  Patna India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bipin Bihari","family":"Mishra","sequence":"additional","affiliation":[{"name":"Department of Virology ICMR\u2010Rajendra Memorial Research Institute of Medical Sciences  Patna India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashish","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Virology ICMR\u2010Rajendra Memorial Research Institute of Medical Sciences  Patna India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sindhuprava","family":"Rana","sequence":"additional","affiliation":[{"name":"Department of Biostatistics and Bioinformatics ICMR\u2010National Institute for Research in Environmental Health  Bhopal India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krishna","family":"Pandey","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine ICMR\u2010Rajendra Memorial Research Institute of Medical Sciences  Patna India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3560-9815","authenticated-orcid":false,"given":"Ganesh","family":"Chandra Sahoo","sequence":"additional","affiliation":[{"name":"Department of Virology ICMR\u2010Rajendra Memorial Research Institute of Medical Sciences  Patna India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,2,23]]},"reference":[{"key":"e_1_2_15_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm6120111"},{"key":"e_1_2_15_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2009.06.001"},{"key":"e_1_2_15_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/v16030416"},{"key":"e_1_2_15_5_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.78.21.11451\u201011460.2004"},{"key":"e_1_2_15_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470\u20102045(09)70096\u20108"},{"key":"e_1_2_15_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(64)91524\u20107"},{"key":"e_1_2_15_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12875\u2010019\u20100954\u20103"},{"key":"e_1_2_15_9_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1011806108"},{"key":"e_1_2_15_10_1","doi-asserted-by":"publisher","DOI":"10.1128\/cmr.00044\u201010"},{"key":"e_1_2_15_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2018.03.001"},{"issue":"4","key":"e_1_2_15_12_1","first-page":"234","article-title":"Prospective Study of the Natural History of Infectious Mononucleosis Caused by Epstein\u2010Barr Virus","volume":"14","author":"Rea T. D.","year":"2001","journal-title":"Journal of the American Board of Family Practice"},{"key":"e_1_2_15_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/bcr\u20102016\u2010218405"},{"key":"e_1_2_15_14_1","volume-title":"StatPearls [Internet]","author":"Hoover K.","year":"2024"},{"key":"e_1_2_15_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2018.06.149"},{"key":"e_1_2_15_16_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2017.19872"},{"key":"e_1_2_15_17_1","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines11061060"},{"key":"e_1_2_15_18_1","doi-asserted-by":"publisher","DOI":"10.3390\/v16050680"},{"key":"e_1_2_15_19_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.75.6.2879\u20102890.2001"},{"key":"e_1_2_15_20_1","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.01533\u201024"},{"key":"e_1_2_15_21_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13246208"},{"key":"e_1_2_15_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc2888"},{"key":"e_1_2_15_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/978\u20103\u2010030\u201003502\u20100_3"},{"key":"e_1_2_15_24_1","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.01268\u201023"},{"key":"e_1_2_15_25_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12889\u2010024\u201018918\u20108"},{"key":"e_1_2_15_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.22881"},{"key":"e_1_2_15_27_1","doi-asserted-by":"publisher","DOI":"10.2174\/0113892010310175250618134149"},{"key":"e_1_2_15_28_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01664\u201019"},{"key":"e_1_2_15_29_1","doi-asserted-by":"publisher","DOI":"10.3791\/58950"},{"key":"e_1_2_15_30_1","volume-title":"Human T\u2010Cell Lymphotropic Virus","author":"Bryan E. S.","year":"2024"},{"key":"e_1_2_15_31_1","article-title":"Kaposi's Sarcoma\u2010Associated Herpesvirus (KSHV)\u2010Associated Disease in the AIDS Patient: An Update","author":"Dittmer D. P.","year":"2019","journal-title":"Cancer"},{"key":"e_1_2_15_32_1","doi-asserted-by":"publisher","DOI":"10.25270\/con.2020.06.00006"},{"key":"e_1_2_15_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2018.04.4242"},{"key":"e_1_2_15_34_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.16.1.1\u201017.2003"},{"key":"e_1_2_15_35_1","doi-asserted-by":"publisher","DOI":"10.15698\/mic2016.09.527"},{"key":"e_1_2_15_36_1","doi-asserted-by":"publisher","DOI":"10.1017\/CBO9780511545313.054"},{"key":"e_1_2_15_37_1","doi-asserted-by":"publisher","DOI":"10.3390\/v6114178"},{"key":"e_1_2_15_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.coviro.2016.07.011"},{"key":"e_1_2_15_39_1","doi-asserted-by":"publisher","DOI":"10.1093\/jpids\/piu070"},{"key":"e_1_2_15_40_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jis677"},{"key":"e_1_2_15_41_1","doi-asserted-by":"publisher","DOI":"10.31557\/APJCP.2023.24.7.2207"},{"key":"e_1_2_15_42_1","doi-asserted-by":"publisher","DOI":"10.4103\/0253\u20107184.81257"},{"key":"e_1_2_15_43_1","doi-asserted-by":"publisher","DOI":"10.1155\/2005\/450574"},{"key":"e_1_2_15_44_1","unstructured":"Center for Substance Abuse Treatment. \u201cAddressing Viral Hepatitis in People With Substance Use Disorders. Rockville (MD): Substance Abuse and Mental Health Services Administration (US); 2011. (Treatment Improvement Protocol (TIP) Series No. 53.) 2 Screening for Viral Hepatitis\u201d https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK92029\/."},{"key":"e_1_2_15_45_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.42.8.3381\u20103387.2004"},{"key":"e_1_2_15_46_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01368\u201007"},{"key":"e_1_2_15_47_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.184.1.283"},{"key":"e_1_2_15_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jim.2010.02.015"},{"key":"e_1_2_15_49_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid1604.091278"},{"key":"e_1_2_15_50_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13073\u2010020\u201000727\u20104"},{"key":"e_1_2_15_51_1","doi-asserted-by":"publisher","DOI":"10.3390\/v15010129"},{"key":"e_1_2_15_52_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2022.1003047"},{"key":"e_1_2_15_53_1","doi-asserted-by":"publisher","DOI":"10.3390\/v11090830"},{"key":"e_1_2_15_54_1","article-title":"(IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, No. 90.) 1, Human Papillomavirus (HPV)","author":"IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Human Papillomaviruses. Lyon (FR): International Agency for Research on Cancer","year":"2007","journal-title":"Infection"},{"key":"e_1_2_15_55_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD015730"},{"key":"e_1_2_15_56_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v20.i20.6262"},{"key":"e_1_2_15_57_1","doi-asserted-by":"publisher","DOI":"10.2147\/IDR.S375624"},{"key":"e_1_2_15_58_1","volume-title":"PDQ Cancer Information Summaries","author":"PDQ Adult Treatment Editorial Board","year":"2002"},{"key":"e_1_2_15_59_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers14020422"},{"key":"e_1_2_15_60_1","doi-asserted-by":"publisher","DOI":"10.1586\/edm.11.40"},{"key":"e_1_2_15_61_1","volume-title":"Adult T\u2010Cell Leukemia","author":"Durer C.","year":"2024"},{"key":"e_1_2_15_62_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2020.01207"},{"key":"e_1_2_15_63_1","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofab525"},{"key":"e_1_2_15_64_1","doi-asserted-by":"publisher","DOI":"10.7150\/ijms.43079"},{"key":"e_1_2_15_65_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc3449"},{"key":"e_1_2_15_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2012.06.083"},{"key":"e_1_2_15_67_1","doi-asserted-by":"publisher","DOI":"10.1038\/onc.2010.537"},{"key":"e_1_2_15_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.virusres.2009.06.008"},{"key":"e_1_2_15_69_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc1452"},{"key":"e_1_2_15_70_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-71843-4_15"},{"key":"e_1_2_15_71_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.molpharmaceut.2c01080"},{"key":"e_1_2_15_72_1","doi-asserted-by":"publisher","DOI":"10.3390\/v16030416"},{"key":"e_1_2_15_73_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41579\u2010018\u20100064\u20106"},{"key":"e_1_2_15_74_1","doi-asserted-by":"publisher","DOI":"10.1186\/1750\u20109378\u20109\u201038"},{"key":"e_1_2_15_75_1","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines11061060"},{"key":"e_1_2_15_76_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2016.02.622"},{"key":"e_1_2_15_77_1","doi-asserted-by":"publisher","DOI":"10.5501\/wjv.v13.i1.89469"},{"key":"e_1_2_15_78_1","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines9070718"},{"key":"e_1_2_15_79_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.livres.2024.05.004"},{"key":"e_1_2_15_80_1","doi-asserted-by":"publisher","DOI":"10.3390\/v2092037"}],"container-title":["Reviews in Medical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rmv.70121","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/rmv.70121","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rmv.70121","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T05:10:19Z","timestamp":1774588219000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/rmv.70121"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,23]]},"references-count":79,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["10.1002\/rmv.70121"],"URL":"https:\/\/doi.org\/10.1002\/rmv.70121","archive":["Portico"],"relation":{},"ISSN":["1052-9276","1099-1654"],"issn-type":[{"value":"1052-9276","type":"print"},{"value":"1099-1654","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,23]]},"assertion":[{"value":"2025-10-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-17","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-23","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70121"}}