{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,15]],"date-time":"2023-11-15T01:41:46Z","timestamp":1700012506732},"reference-count":13,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2006,6,16]],"date-time":"2006-06-16T00:00:00Z","timestamp":1150416000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Statistics in Medicine"],"published-print":{"date-parts":[[2007,2,28]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>When studying the effect of a transient exposure on the risk of a rare illness, for time and cost effectiveness it is desirable to follow a cohort of individuals who are \u2018prone\u2019 to the illness over an observation period. In this paper, we present a method of analysis for data arising from such a study. The proposed method can be used to estimate the relative risk of an exposure triggering the illness and the distribution of the time delay from exposure to the onset of illness. The model is extended to include covariate effects and to the situation where there are two types of exposure. For the two types of exposures situation, a model to handle a possible synergism of the exposures is proposed. Finally, the method is applied to study the potential triggers of attacks of Meni\u00e8re's disease. Copyright \u00a9 2006 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/sim.2601","type":"journal-article","created":{"date-parts":[[2006,6,16]],"date-time":"2006-06-16T11:34:02Z","timestamp":1150457642000},"page":"1136-1149","source":"Crossref","is-referenced-by-count":2,"title":["An analysis for a cross\u2010over cohort study with an application to the study of triggers of Meni\u00e8re's disease"],"prefix":"10.1002","volume":"26","author":[{"given":"Agus","family":"Salim","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Niels G.","family":"Becker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jette","family":"M\u00f6ller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne\u2010Charlotte","family":"Hess\u00e9n\u2010S\u00f6derman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,6,16]]},"reference":[{"key":"e_1_2_1_2_2","volume-title":"Statistical Methods in Cancer Research: Volume I\u2014The Analysis of Case\u2013Control Studies","author":"Breslow NE","year":"1980"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a115853"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/sim.4780122409"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.publhealth.21.1.193"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/biostatistics\/kxi037"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200410000-00031"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1023\/A:1010371830131"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.305.6858.865"},{"key":"e_1_2_1_10_2","volume-title":"Statistical Models in Epidemiology","author":"Clayton D","year":"1993"},{"key":"e_1_2_1_11_2","unstructured":"M\u00f6llerJ.Case\u2010crossover studies of the triggering of disease: myocar\u2010 dial infarction and M\u00e9ni\u00e8re's disease. Ph.D. Dissertation Karolinska Institutet Stockholm 2004."},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0258(19990115)18:1<1::AID-SIM961>3.0.CO;2-L"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.ede.0000135177.10332.42"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1093\/biostatistics\/kxh024"}],"container-title":["Statistics in Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fsim.2601","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/sim.2601","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,15]],"date-time":"2023-11-15T01:16:27Z","timestamp":1700010987000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/sim.2601"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,6,16]]},"references-count":13,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2007,2,28]]}},"alternative-id":["10.1002\/sim.2601"],"URL":"https:\/\/doi.org\/10.1002\/sim.2601","archive":["Portico"],"relation":{},"ISSN":["0277-6715","1097-0258"],"issn-type":[{"value":"0277-6715","type":"print"},{"value":"1097-0258","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,6,16]]}}}