{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:55:08Z","timestamp":1786978508647,"version":"build-2736575974"},"reference-count":13,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2010,11,5]],"date-time":"2010-11-05T00:00:00Z","timestamp":1288915200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2010,11,5]],"date-time":"2010-11-05T00:00:00Z","timestamp":1288915200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2010,11,5]],"date-time":"2010-11-05T00:00:00Z","timestamp":1288915200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["wiley.com"],"crossmark-restriction":true},"short-container-title":["Statistics in Medicine"],"published-print":{"date-parts":[[2011,2,20]]},"abstract":"Abstract<\/jats:title>\n Health care interventions that use quality of life or health scores often provide data which are skewed and bounded. The scores are typically formed by adding up numerical responses to a number of questions. Different questions might have different weights, but the scores will be bounded, and are often scaled to the range 0\u2013100. If improvement in health over time is measured, scores will tend to cluster near the \u2018healthy\u2019 or \u2018good\u2019 boundary as time progresses, leading to a skew distribution. Further, some patients will drop\u2010out as time progresses, hence the scores reflect a selected population.<\/jats:p>\n We fit models based on the skew\u2010normal distribution to data from a randomized controlled trial of treatments for sprained ankles, in which scores were recorded at baseline and at 1, 3 and 9 months after injury. We consider the extent to which skewness in the data can be explained by clustering at the boundary via a comparison between a censored normal and a censored skew\u2010normal model.<\/jats:p>\n As this analysis is based on the complete data only, a formula for the bias of the treatment effects due to informative drop\u2010out is given. This allows us to assess under what conditions the conclusions drawn from the complete data might be either reinforced or reversed, when the informative drop\u2010out process is taken into account. Copyright \u00a9 2010 John Wiley & Sons, Ltd.<\/jats:p>","DOI":"10.1002\/sim.4104","type":"journal-article","created":{"date-parts":[[2010,11,7]],"date-time":"2010-11-07T09:33:04Z","timestamp":1289122384000},"page":"368-376","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Modelling bounded health scores with censored skew\u2010normal distributions"],"prefix":"10.1002","volume":"30","author":[{"given":"J. L.","family":"Hutton","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Stanghellini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2010,11,5]]},"reference":[{"key":"e_1_2_9_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/1467-9868.00194"},{"key":"e_1_2_9_3_2","first-page":"76","article-title":"Discussion on \u2018Informative drop\u2010out in longitudinal data analysis\u2019 by Diggle PJ and Kenward MG","volume":"43","author":"Skinner CJ","year":"1994","journal-title":"Applied Statistics"},{"key":"e_1_2_9_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)60206-3"},{"key":"e_1_2_9_5_2","first-page":"226","article-title":"Response and non\u2010response to postal questionnaire follow\u2010up in a clinical trial\u2014a qualitative study of the patient's perspective","volume":"14","author":"Nakash RA","year":"2008","journal-title":"BMC Medical Research Methodology"},{"key":"e_1_2_9_6_2","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7525-5-63"},{"key":"e_1_2_9_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-94-009-5836-4"},{"key":"e_1_2_9_8_2","doi-asserted-by":"publisher","DOI":"10.2307\/2985678"},{"key":"e_1_2_9_9_2","doi-asserted-by":"publisher","DOI":"10.2307\/1912352"},{"key":"e_1_2_9_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/1467-9868.00055"},{"key":"e_1_2_9_11_2","volume-title":"Econometrics Analysis of Cross Section and Panel data","author":"Wooldridge JM","year":"2003"},{"key":"e_1_2_9_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.spl.2007.09.050"},{"key":"e_1_2_9_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/0304-4076(81)90100-7"},{"key":"e_1_2_9_14_2","doi-asserted-by":"publisher","DOI":"10.2307\/2986113"}],"container-title":["Statistics in Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fsim.4104","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fsim.4104","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/sim.4104","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T00:27:15Z","timestamp":1698712035000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/sim.4104"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,11,5]]},"references-count":13,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2011,2,20]]}},"alternative-id":["10.1002\/sim.4104"],"URL":"https:\/\/doi.org\/10.1002\/sim.4104","archive":["Portico"],"relation":{},"ISSN":["0277-6715","1097-0258"],"issn-type":[{"value":"0277-6715","type":"print"},{"value":"1097-0258","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,11,5]]}}}