{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,22]],"date-time":"2023-10-22T21:11:21Z","timestamp":1698009081787},"reference-count":12,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2006,10,12]],"date-time":"2006-10-12T00:00:00Z","timestamp":1160611200000},"content-version":"vor","delay-in-days":7408,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Statistics in Medicine"],"published-print":{"date-parts":[[1986,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In the first seven cases of transfusion\u2010associated acquired immunodeficiency syndrome (TA\u2010AIDS) with completion of blood donor investigations, there was identification of at least one person (a high\u2010risk donor\u2010 HRD) in each donor set who might have transmitted the disease. Using three definitions of an HRD, we estimated the prevalence of HRDs in the overall donor population and used the binomial distribution to calculate the probabilities of finding at least the observed numbers of donor sets with one or more HRDs. These probabilities\u20100.028, 0.007 and 0.014, respectively\u2010allowed us to reject the null hypothesis that the number of cases of TA\u2010AIDS exposed to an HRD was not greater than that expected by chance, based on the total number of donors to which each case was exposed and the estimated proportion of HRDs in the overall donor population. We concluded that there was a statistically significant association between HRDs and TA\u2010AIDS.<\/jats:p>","DOI":"10.1002\/sim.4780050408","type":"journal-article","created":{"date-parts":[[2007,4,24]],"date-time":"2007-04-24T16:14:06Z","timestamp":1177431246000},"page":"355-362","source":"Crossref","is-referenced-by-count":1,"title":["The use of the binomial distribution in establishing an association between high\u2010risk donors and transfusion\u2010associated aids"],"prefix":"10.1002","volume":"5","author":[{"given":"Jonathan E.","family":"Kaplan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lawrence B.","family":"Schonberger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kung\u2010Jong","family":"Lui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,10,12]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198401123100201"},{"key":"e_1_2_1_3_2","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1001\/jama.1985.03360060072028","article-title":"Infection with HTLV\u2010III\/LAV and transfusion\u2010associated acquired immunodeficiency syndrome","volume":"254","author":"Jaffe H. W.","year":"1985","journal-title":"Journal of the American Medical Association"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.6324345"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(84)92444-9"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(84)91933-0"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198411153112001"},{"key":"e_1_2_1_8_2","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1001\/jama.1985.03350260073029","article-title":"Screening test for HTLV\u2010III (AIDS agent) antibodies: specificity, sensitivity, and applications","volume":"253","author":"Weiss S. H.","year":"1985","journal-title":"Journal of the American Medical Association"},{"key":"e_1_2_1_9_2","first-page":"1","article-title":"Provisional Public Health Service inter\u2010agency recommendations for screening donated blood and plasma for antibody to the virus causing acquired immunodeficiency syndrome","volume":"34","author":"Centers for Disease Control","year":"1985","journal-title":"Morbidity and Mortality Weekly Report"},{"key":"e_1_2_1_10_2","first-page":"375","article-title":"Results of Human T\u2010Lymphotropic Virus type III test kits reported from blood collection centers\u2010United States, April 22,\u2010May 19, 1985","volume":"34","author":"Centers for Disease Control","year":"1985","journal-title":"Morbidity and Mortality Weekly Report"},{"key":"e_1_2_1_11_2","first-page":"101","article-title":"Prevention of acquired immune deficiency syndrome (AIDS): report of inter\u2010agency recommendations","volume":"32","author":"Centers for Disease Control","year":"1983","journal-title":"Morbidity and Mortality Weekly Report"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.6328663"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a113496"}],"container-title":["Statistics in Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fsim.4780050408","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/sim.4780050408","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,22]],"date-time":"2023-10-22T00:29:45Z","timestamp":1697934585000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/sim.4780050408"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1986,7]]},"references-count":12,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1986,7]]}},"alternative-id":["10.1002\/sim.4780050408"],"URL":"https:\/\/doi.org\/10.1002\/sim.4780050408","archive":["Portico"],"relation":{},"ISSN":["0277-6715","1097-0258"],"issn-type":[{"value":"0277-6715","type":"print"},{"value":"1097-0258","type":"electronic"}],"subject":[],"published":{"date-parts":[[1986,7]]}}}