{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T16:47:46Z","timestamp":1792601266388,"version":"4.5.0"},"reference-count":34,"publisher":"Wiley","issue":"23-24","license":[{"start":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T00:00:00Z","timestamp":1792108800000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Statistics in Medicine"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>In a cancer clinical trial with an immunotherapy, the treatment often becomes effective after a certain delay time. It is well known that traditional log\u2010rank test no longer provides optimal power in this case. There has been a great interest to search for a more powerful test to detect a truly effective immunotherapy treatment. In this paper, we propose a new testing method based on the maximum value of a set of 0\u20131 weighted log\u2010rank test statistics and establish useful theoretical results of the relevant test statistics. Extensive simulation studies are conducted to examine the empirical performance of the proposed method. An analysis of the real data from a non\u2010small\u2010cell lung cancer clinical trial is also carried out to further demonstrate the usefulness of the proposed test method.<\/jats:p>\n                  <jats:p>\n                    <jats:bold>Trial Registration:<\/jats:bold>\n                    <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/clinicaltrials.gov\">ClinicalTrials.gov<\/jats:ext-link>\n                    ID: NCT01903993, NCT02008227\n                  <\/jats:p>","DOI":"10.1002\/sim.70773","type":"journal-article","created":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T04:05:17Z","timestamp":1792209917000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Max 0\u20131 Weighted Log\u2010Rank Test for Time\u2010to\u2010Event Data With Random Delayed Treatment 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