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Strangely, anti-desmoglein 1 antibodies were positive, although no pemphigus-like features were found. Indirect immunofluorescence showed IgG reactivity with dermal side of 1 M NaCl-split skin. Immunoblotting showed positive reactivity with the 200 kDa laminin gamma-1 but not with type VII collagen. After the administration of prednisolone 20 mg\/day, bullous lesions cleared within 2 weeks.<\/jats:p>","DOI":"10.1002\/ski2.101","type":"journal-article","created":{"date-parts":[[2022,2,11]],"date-time":"2022-02-11T16:53:32Z","timestamp":1644598412000},"source":"Crossref","is-referenced-by-count":0,"title":["A Case of Anti-Laminin Gamma-1 (P200) Pemphigoid with Bullous Lesions on the Lips, Hands and Feet Showing Antibodies to Desmoglein 1"],"prefix":"10.1093","volume":"2","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5295-889X","authenticated-orcid":false,"given":"F.","family":"Kaneko","sequence":"first","affiliation":[{"name":"Dermatology Unit, Southern TOHOKU General Hospital, Southern TOHOKU Research Institute for Neuroscience , Koriyama ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Ozasa","sequence":"additional","affiliation":[{"name":"Dermatology Unit, Southern TOHOKU General Hospital, Southern TOHOKU Research Institute for Neuroscience , Koriyama ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Togashi","sequence":"additional","affiliation":[{"name":"Dermatology Unit, Southern TOHOKU General Hospital, Southern TOHOKU Research Institute for Neuroscience , Koriyama ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2022,2,11]]},"reference":[{"key":"2025010818055134600_ski2101-bib-0001","first-page":"1483","article-title":"Clinical guidelines of pemphigoid (including epidermolysis bullosa acquisita)","volume":"127","author":"Ujiie","year":"2017","journal-title":"Jpn J Dermatol"},{"issue":"8","key":"2025010818055134600_ski2101-bib-0002","doi-asserted-by":"publisher","first-page":"2800","DOI":"10.1073\/pnas.o809230106","article-title":"Anti-laminin gamma-1 pemphigoid","volume":"106","author":"Dainichi","year":"2009","journal-title":"Proc Natl Acad Sci USA"},{"key":"2025010818055134600_ski2101-bib-0003","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1111\/j.1346-8138.2009.00793.x","article-title":"From anti-p200 pemphigoid to anti-laminin gamma1 pemphigoid","volume":"37","author":"Dainichi","year":"2010","journal-title":"J Dermatol"},{"key":"2025010818055134600_ski2101-bib-0004","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1001\/jamadermatol.2016.1099","article-title":"Laboratory diagnosis and clinical profile of anti-p200 pemphigoid","volume":"152","author":"Meijer","year":"2016","journal-title":"JAMA Dermatol"},{"key":"2025010818055134600_ski2101-bib-0005","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2019.02466","article-title":"Anti-p200 pemphigoid: a systematic review","volume":"10","author":"Kridin","year":"2019","journal-title":"Front Immunol"},{"key":"2025010818055134600_ski2101-bib-0006","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1007\/s12016-017-8633-4","article-title":"Autoimmune subepidermal bullous diseases of the skin and mucosae: clinical features, diagnosis, and management","volume":"54","author":"Amber","year":"2018","journal-title":"Clin Rev Allergy Immunol"}],"container-title":["Skin Health and Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ski2.101","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ski2.101","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/skinhd\/article-pdf\/2\/1\/ski2.101\/59726831\/skinhd_2_1_e101.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/skinhd\/article-pdf\/2\/1\/ski2.101\/59726831\/skinhd_2_1_e101.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,8]],"date-time":"2025-01-08T18:05:59Z","timestamp":1736359559000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/skinhd\/article\/doi\/10.1002\/ski2.101\/7750113"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2,11]]},"references-count":6,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,3,1]]}},"URL":"https:\/\/doi.org\/10.1002\/ski2.101","relation":{},"ISSN":["2690-442X"],"issn-type":[{"type":"electronic","value":"2690-442X"}],"subject":[],"published-other":{"date-parts":[[2022,3]]},"published":{"date-parts":[[2022,2,11]]},"article-number":"ski2.101"}}