{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T18:03:56Z","timestamp":1790013836554,"version":"4.0.1"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2024,10,12]],"date-time":"2024-10-12T00:00:00Z","timestamp":1728691200000},"content-version":"vor","delay-in-days":506,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"This research received no specific grant from any funding agency in the public, commercial, or not-for-profit sectors"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Sclerema neonatorum (SN) is a rare condition of neonatal panniculitis with a poor prognosis and a high fatality rate. It clinically presents as hardening of the skin and subcutaneous adipose tissue extending throughout the body, sparing the fat-free soles, palms, and genitalia. SN typically affects gravely ill, preterm neonates in the first week of life and diagnosis is often clinical. We report a case of an eight-day-old premature infant diagnosed with early-onset neonatal sepsis who presented with clinical and histopathological features of SN. Despite early treatment of the sepsis with intravenous antibiotics and the SN with a topical corticosteroid cream and moisturiser, the infant died on the twelfth day of life.<\/jats:p>","DOI":"10.1002\/ski2.255","type":"journal-article","created":{"date-parts":[[2023,5,25]],"date-time":"2023-05-25T07:09:41Z","timestamp":1684998581000},"source":"Crossref","is-referenced-by-count":2,"title":["Sclerema Neonatorum in a Premature Newborn: A Case Report"],"prefix":"10.1093","volume":"3","author":[{"given":"Rima","family":"Alhalabi","sequence":"first","affiliation":[{"name":"Department of Dermatology and Venereology, Damascus University , Damascus ,","place":["Syria"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riham","family":"Salloum","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology, Damascus University , Damascus ,","place":["Syria"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dima","family":"Alhalabi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Children's University Hospital, Faculty of Medicine, Damascus University , Damascus ,","place":["Syria"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Youlla","family":"Oun","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology, Damascus University , Damascus ,","place":["Syria"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Abudeeb","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology, Damascus University , Damascus ,","place":["Syria"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judy","family":"Kikhia","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Syrian Private University , Damascus ,","place":["Syria"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manal","family":"Mouhamad","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology, Damascus University , Damascus ,","place":["Syria"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,5,25]]},"reference":[{"issue":"7","key":"2025010818122776400_ski2255-bib-0001","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1038\/jp.2008.33","article-title":"Sclerema neonatorum: a review of nomenclature, clinical presentation, histological features, differential diagnoses and management","volume":"28","author":"Zeb","year":"2008","journal-title":"J Perinatol"},{"issue":"4","key":"2025010818122776400_ski2255-bib-0002","doi-asserted-by":"publisher","first-page":"356","DOI":"10.1111\/j.1529-8019.2010.01336.x","article-title":"Panniculitis in 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