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Data from a previous publication were analyzed as a validation. Surveillance, Epidemiology and End Results Program data were also used for comparison.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Relative tumour density (RTD) of melanoma in men and women exhibits a moderate head-to-toe linear gradient, with the upper body sites showing higher density than the lower body sites in general. In particular, the ear and face show the highest RTD while the least UVR (ultraviolet radiation)-exposed buttock, abdomen and groin have the lowest, followed by the thigh and lower legs. The trend is similar in both sexes, but more obvious for men.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>It was well documented that the trunk and lower legs are the most frequently diagnosed sites for men and women, respectively. However, when the surface area is considered, the melanoma distribution exhibits a rough head-to-toe gradient, which perhaps reflects a combined effect of solar UVR and clothing coverage. UVR protection on the face and ear should be emphasized as these are the sites with the highest RTDs.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ski2.463","type":"journal-article","created":{"date-parts":[[2024,11,2]],"date-time":"2024-11-02T12:38:48Z","timestamp":1730551128000},"source":"Crossref","is-referenced-by-count":0,"title":["A Retrospective Single-Institute Study Reveals a Vertical Gradient of the Density of Cutaneous Melanoma from Head to Toe"],"prefix":"10.1093","volume":"4","author":[{"given":"Meryl","family":"Musicante","sequence":"first","affiliation":[{"name":"College of Medicine, University of Tennessee Health Science Center , Memphis, Tennessee ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James","family":"Ferrer","sequence":"additional","affiliation":[{"name":"Department of Dermatology, College of Medicine, University of Tennessee Health Science Center , Memphis, Tennessee 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