{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T04:09:00Z","timestamp":1778731740932,"version":"3.51.4"},"reference-count":38,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2025,1,11]],"date-time":"2025-01-11T00:00:00Z","timestamp":1736553600000},"content-version":"vor","delay-in-days":53,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100013126","name":"Psoriasis Association","doi-asserted-by":"publisher","award":["PhD Studentship \/ R 123115"],"award-info":[{"award-number":["PhD Studentship \/ R 123115"]}],"id":[{"id":"10.13039\/100013126","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Sedentary behaviour has a detrimental effect on health independent of the amount of physical activity undertaken. Despite the association of cardiometabolic and psychosocial comorbidities with psoriasis, how physical behaviour influences health outcomes in patients with psoriasis is poorly understood.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>We hypothesized that objective measurement of physical behaviour, using wearable digital technology, would have utility in understanding the clinical impact of an exercise intervention designed in partnership with patients with psoriasis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Fourteen patients with psoriasis completed a 20-week study. During weeks 1\u201310, participants followed an incrementally progressive, exercise intervention, followed by independent activities during weeks 11\u201320. Accelerometers (GENEActiv Original) and pedometers recorded physical behaviour. Evaluation at week-0, -10, and -20 included assessment of psoriasis, cardiometabolic disease\/risk, psychological health and functional capacity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Our intervention supported significantly increased physical activity, including moderate\u2013vigorous physical activity (p = 0.04) and step count (p = 0.04). We also observed a significant association between physical activity and psoriasis area and severity index (PASI)-50 response (p = 0.01) and psychosocial functioning (p = 0.029) together with a significant negative correlation between step count and psoriasis severity (p = 0.012). We observed no change in total waking hour sedentary behaviour.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Objective measurement of physical behaviour, using wearable digital technologies, offers a mechanism to further understand the clinical impact of lifestyle behaviour interventions. Crucially, despite increased levels of physical activity, we observed no change in total waking hour sedentary time. Further investigation is required to establish how modification of physical behaviour could offer an adjuvant management strategy for patients with psoriasis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ski2.473","type":"journal-article","created":{"date-parts":[[2024,11,19]],"date-time":"2024-11-19T15:14:23Z","timestamp":1732029263000},"source":"Crossref","is-referenced-by-count":1,"title":["Using Wearable Technology to Objectively Investigate Physical Behaviour and Determine Health Outcomes of a Physical Activity Intervention in Patients with Psoriasis"],"prefix":"10.1093","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9571-8274","authenticated-orcid":false,"given":"Rory","family":"Sheppard","sequence":"first","affiliation":[{"name":"Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, The University of Manchester , Manchester ,","place":["UK"]},{"name":"The Dermatology Centre, Salford Royal Hospital, Manchester Academic Health Science Centre, The University of Manchester , Manchester ,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weh K.","family":"Gan","sequence":"additional","affiliation":[{"name":"The Dermatology Centre, Salford Royal Hospital, Manchester Academic Health Science Centre, The University of Manchester , Manchester ,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gladys L.","family":"Onambele-Pearson","sequence":"additional","affiliation":[{"name":"Department of Sport and Exercise Sciences, Manchester Metropolitan University , Manchester ,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1538-445X","authenticated-orcid":false,"given":"Helen S.","family":"Young","sequence":"additional","affiliation":[{"name":"Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, The University of Manchester , Manchester ,","place":["UK"]},{"name":"The Dermatology Centre, Salford Royal Hospital, Manchester Academic Health Science Centre, The University of Manchester , Manchester ,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,11,19]]},"reference":[{"issue":"6","key":"2025112606022233700_ski2473-bib-0001","doi-asserted-by":"publisher","first-page":"1094","DOI":"10.1111\/bjd.18979","article-title":"What are the barriers to physical activity in patients with chronic plaque psoriasis?","volume":"183","author":"Auker","year":"2020","journal-title":"Br J Dermatol"},{"issue":"Suppl ment_4","key":"2025112606022233700_ski2473-bib-0002","doi-asserted-by":"publisher","DOI":"10.1093\/bjd\/ljad113.362","article-title":"PS10 Can an aerobic exercise intervention for patients with psoriasis improve health outcomes and support lifestyle behaviour change?","volume":"188","author":"Sheppard","year":"2023","journal-title":"Br J Dermatol"},{"key":"2025112606022233700_ski2473-bib-0003","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1016\/j.physbeh.2019.02.041","article-title":"Sedentary behavior and physiological health determinants in male and female college students","volume":"204","author":"Vainshelboim","year":"2019","journal-title":"Physiol Behav"},{"issue":"10051","key":"2025112606022233700_ski2473-bib-0004","doi-asserted-by":"publisher","first-page":"1302","DOI":"10.1016\/s0140-6736(16)30370-1","article-title":"Does physical activity attenuate, or even eliminate, the detrimental association of sitting time with mortality? 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