{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T16:53:20Z","timestamp":1791996800226,"version":"4.4.0"},"reference-count":12,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2024,10,12]],"date-time":"2024-10-12T00:00:00Z","timestamp":1728691200000},"content-version":"vor","delay-in-days":988,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Coronavirus disease 2019 (COVID-19) disease and vaccines have been associated to various skin reactions, which are mostly similar amongst them. New onset of vitiligo and hypopigmentations have been described following COVID-19 vaccination, but never after COVID-19 infection.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>We present the case of a 45-year-old woman, who developed vitiligo 2 weeks after COVID-19 disease. Skin lesions stabilized after 1 month of initial spreading.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Vitiligo is a relatively common acquired pigmentary disorder, possibly caused by a T CD8+ cell-mediated autoimmune process, which may be enhanced after the immune activation of COVID-19 disease. Molecular mimicry and bystander activation have been advocated as possible pathogenic mechanisms of vitiligo after COVID-19 vaccination. The same mechanisms may also be involved as possible vitiligo triggers during COVID-19 disease.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Clinicians should be aware of this possible autoimmune cutaneous reaction to COVID-19 disease.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1002\/ski2.86","type":"journal-article","created":{"date-parts":[[2022,1,29]],"date-time":"2022-01-29T07:48:59Z","timestamp":1643442539000},"source":"Crossref","is-referenced-by-count":21,"title":["New-Onset Vitiligo Following COVID-19 Disease"],"prefix":"10.1093","volume":"2","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6373-8801","authenticated-orcid":false,"given":"A.","family":"Herzum","sequence":"first","affiliation":[{"name":"Department of Dermatology, Di.S.Sal., San Martino Polyclinic Hospital IRCCS, University of Genoa , Genoa ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Micalizzi","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Di.S.Sal., San Martino Polyclinic Hospital IRCCS, University of Genoa , Genoa ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. F.","family":"Molle","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Di.S.Sal., San Martino Polyclinic Hospital IRCCS, University of Genoa , Genoa ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Parodi","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Di.S.Sal., San Martino Polyclinic Hospital IRCCS, University of Genoa , Genoa ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,1,28]]},"reference":[{"key":"2025010818053016900_ski286-bib-0001","doi-asserted-by":"crossref","DOI":"10.1002\/ski2.20","article-title":"A systematic review of dermatologic manifestations among adult patients with COVID-19 diagnosis","volume":"1","author":"Schwartzberg","year":"2021","journal-title":"Skin Health Dis"},{"key":"2025010818053016900_ski286-bib-0002","doi-asserted-by":"crossref","first-page":"1916","DOI":"10.3390\/v13101916","article-title":"Identification, mechanism, and treatment of skin lesions in COVID-19: a review","volume":"13","author":"Fern\u00e1ndez-L\u00e1zaro","year":"2021","journal-title":"Viruses"},{"key":"2025010818053016900_ski286-bib-0003","article-title":"Cutaneous reactions to COVID-19 vaccine at the dermatology primary care","author":"Burlando","year":"2021","journal-title":"Immunity Inflamm Disease"},{"key":"2025010818053016900_ski286-bib-0004","article-title":"Cutaneous findings following COVID-19 vaccination: review of world literature and own experience","author":"Gambichler","year":"2021","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"2025010818053016900_ski286-bib-0005","doi-asserted-by":"crossref","DOI":"10.1002\/ccr3.4865","article-title":"New-onset vitiligo following mRNA-1273 (Moderna) COVID-19 vaccination","volume":"9","author":"Kaminetsky","year":"2021","journal-title":"Clin Case Rep"},{"key":"2025010818053016900_ski286-bib-0006","article-title":"Vitiligo in a COVID-19-vaccinated patient with ulcerative colitis: coincidence?","author":"Aktas","year":"2021","journal-title":"Clin Exp Dermatol"},{"key":"2025010818053016900_ski286-bib-0007","article-title":"Sudden onset of vitiligo after COVID-19 vaccine","author":"Ciccarese","year":"2021","journal-title":"Dermatol Ther"},{"key":"2025010818053016900_ski286-bib-0008","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.jaad.2021.03.092","article-title":"Cutaneous reactions reported after Moderna and Pfizer COVID-19 vaccination: a registry-based study of 414 cases","volume":"85","author":"McMahon","year":"2021","journal-title":"J Am Acad Dermatol"},{"key":"2025010818053016900_ski286-bib-0009","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1111\/exd.14407","article-title":"Does autoimmune vitiligo protect against COVID-19 disease?","volume":"30","author":"Post","year":"2021","journal-title":"Exp Dermatol"},{"key":"2025010818053016900_ski286-bib-0010","article-title":"Lichen planus flare following COVID-19 vaccination: a case report","volume":"2021","author":"Herzum","journal-title":"Clin Case Rep"},{"issue":"1","key":"2025010818053016900_ski286-bib-0011","doi-asserted-by":"publisher","DOI":"10.23736\/s2784-8671.19.06488-5","article-title":"Cutaneous manifestations of HAV, HBV, HCV","volume":"156","author":"Cozzani","year":"2021","journal-title":"Ital J Dermatol Venerol"},{"key":"2025010818053016900_ski286-bib-0012","doi-asserted-by":"crossref","DOI":"10.1002\/ski2.6","article-title":"Covid-19 dermatoses: acral vesicular pattern evolving into bullous pemphigoid","volume":"1","author":"Goon","year":"2021","journal-title":"Skin Health Dis"}],"container-title":["Skin Health and 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