{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,15]],"date-time":"2024-09-15T13:28:00Z","timestamp":1726406880755},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2023,1,4]],"date-time":"2023-01-04T00:00:00Z","timestamp":1672790400000},"content-version":"vor","delay-in-days":3321,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,12,1]]},"abstract":"Abstract<\/jats:title>\n \n Introduction<\/jats:title>\n Capsular contraction (CC) occurring with inflatable penile prosthesis (IPP) reservoirs has been reported by urologists as a cause of autoinflation. The concept of CC occurring around IPP cylinders has not been studied.<\/jats:p>\n <\/jats:sec>\n \n Aims<\/jats:title>\n Herein we report a case of CC occurring with nonlength-expanding IPP cylinders, resulting in an S-shaped deformity.<\/jats:p>\n <\/jats:sec>\n \n Main Outcome Measures<\/jats:title>\n We sought to report a novel cause of S-shaped deformity in patients after IPP surgery.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n We reviewed a recent clinical case and conducted a literature review on capsular scar formation in prosthetic surgery. We also conducted a literature review of the inflammatory cascade related with prosthetic surgery.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n Capsular contracture of nonlength-expanding cylinders resulting in S-shaped deformity has not been previously reported. The role of certain inflammatory markers seems to play a common role of capsular contracture in the penis and other prosthetic implantation sites.<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Capsular contractures around the cylinders of an IPP can cause deformity, even in patients who have appropriately sized, nonlength-expanding cylinders. A better understanding is needed regarding the mechanical properties of the tunica albuginea and the inflammatory cascade associated with penile implant surgery. This case represents an argument for early and aggressive postoperative inflation of the IPP. Future studies should evaluate the role of inflammation modulators as adjuvant therapy after IPP surgery.<\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/sm2.14","type":"journal-article","created":{"date-parts":[[2013,10,12]],"date-time":"2013-10-12T02:34:26Z","timestamp":1381545266000},"page":"95-98","source":"Crossref","is-referenced-by-count":4,"title":["Capsular Contraction with S-Shaped Deformity of Nonlength-Expanding Inflatable Penile Prosthesis Cylinders: Management and Prevention Strategies"],"prefix":"10.1093","volume":"1","author":[{"given":"Edward","family":"Karpman","sequence":"first","affiliation":[{"name":"El Camino Urology Medical Group , Mountain View, CA , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerard","family":"Henry","sequence":"additional","affiliation":[{"name":"Regional Urology , Shreveport, CA , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2013,12,1]]},"reference":[{"key":"2023011903535621600_bb0010","doi-asserted-by":"crossref","first-page":"1212","DOI":"10.1111\/j.1743-6109.2011.02525.x","article-title":"Laparascopic capsulotomy to treat autoinflation of inflatable penile prostheses","volume":"9","author":"Abbosh","year":"2012","journal-title":"J Sex Med"},{"issue":"4 Pt 1","key":"2023011903535621600_bb0015","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1016\/S0022-5347(05)64477-1","article-title":"The mentor Alpha 1 penile prosthesis with reservoir lock-out valve: Effective prevention of auto-inflation with improved capability for ectopic reservoir placement","volume":"168","author":"Wilson","year":"2002","journal-title":"J Urol"},{"key":"2023011903535621600_bb0020","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1016\/j.eururo.2006.10.026","article-title":"Penile length alterations 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uncontrolled lengthening (the S-shaped deformity)","volume":"155","author":"Wilson","year":"1996","journal-title":"J Urol"},{"key":"2023011903535621600_bb0040","doi-asserted-by":"crossref","first-page":"1808","DOI":"10.1097\/PRS.0b013e3181bf7f26","article-title":"Capsular contractures: a systematic review","volume":"124","author":"Araco","year":"2009","journal-title":"Plast Reconstr Surg"},{"key":"2023011903535621600_bb0045","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1097\/00000637-200044040-00006","article-title":"Periprosthetic breast capsules contain the fibrogenic cytokines TGF-beta1 and TGF-beta2, suggesting possible new treatment approaches","volume":"44","author":"Kuhn","year":"2000","journal-title":"Ann Plast Surg"},{"key":"2023011903535621600_bb0050","doi-asserted-by":"crossref","first-page":"2077","DOI":"10.1111\/j.1743-6109.2010.01790.x","article-title":"Pentoxifylline attenuates transforming growth factor-beta1-stimulated collagen deposition and elastogenesis 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