{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T17:56:05Z","timestamp":1785520565406,"version":"3.56.0"},"reference-count":43,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,9,5]],"date-time":"2019-09-05T00:00:00Z","timestamp":1567641600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81270460"],"award-info":[{"award-number":["81270460"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81470815"],"award-info":[{"award-number":["81470815"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Stress and Health"],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The association between chronic psychological stress and uterine fibroids (UFs) risk remains unclear. In this study, a meta\u2010analysis of observational studies was performed to explore the reported association between them. A literature search was performed in PubMed, EMBASE, and Web of Science to identify relevant published articles. A random\u2010effect model was used to examine pooled odds ratio (OR) and 95% confidence interval (CI). Additionally, subgroup analyses and two\u2010stage random\u2010effect dose\u2013response meta\u2010analysis were performed. A total of six articles with seven studies were included in this meta\u2010analysis. For the highest versus lowest category of chronic psychological stress, the pooled OR was 1.24 (95% CI [1.15, 1.34]; <jats:italic>p<\/jats:italic> = .000). Through subgroup analyses, we found a positive association between chronic psychological stress and UFs risk especially in non\u2010Hispanic Blacks studies (OR, 1.24, 95% CI [1.14, 1.34], <jats:italic>p<\/jats:italic> = .000). When evaluating for a dose\u2013response, we found a weak correlation between chronic psychological stress and UFs risk, especially for the severe (OR, 1.17, 95% CI [1.07, 1.29]) and very severe (OR, 1.23, 95% CI [1.07, 1.41]) categories. Our meta\u2010analysis shows a statistically significant association between chronic psychological stress and UFs risk particularly for non\u2010Hispanic Blacks. Interventions aiming to reduce chronic psychological stress may be useful to decrease the prevalence of UFs.<\/jats:p>","DOI":"10.1002\/smi.2895","type":"journal-article","created":{"date-parts":[[2019,8,27]],"date-time":"2019-08-27T05:37:57Z","timestamp":1566884277000},"page":"585-594","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["The association between chronic psychological stress and uterine fibroids risk: A meta\u2010analysis of observational studies"],"prefix":"10.1002","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7649-4340","authenticated-orcid":false,"given":"Hao","family":"Qin","sequence":"first","affiliation":[{"name":"School of Basic Medicine Qingdao University  Qingdao China"},{"name":"School of Public Health &amp; Management Weifang Medical University  Weifang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhijuan","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine Weifang Medical University  Weifang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"V\u00e1squez","sequence":"additional","affiliation":[{"name":"School of Public Health, University at Albany State University of New York  New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luo","family":"Xu","sequence":"additional","affiliation":[{"name":"School of Basic Medicine Qingdao University  Qingdao China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,9,5]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psyneuen.2018.08.034"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2003.99"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0438019100"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.94.8.1378"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2011.12.002"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.2147\/CEOR.S139335"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms19123869"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmv030"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0197-2456(86)90046-2"},{"key":"e_1_2_9_11_1","doi-asserted-by":"crossref","unstructured":"Dos Santos E. 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