{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T20:44:13Z","timestamp":1777927453970,"version":"3.51.4"},"reference-count":37,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,10,6]],"date-time":"2020-10-06T00:00:00Z","timestamp":1601942400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Stress and Health"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Fibromyalgia (FM) was frequently observed in patients with rheumatoid arthritis (RA). We aimed to evaluate the differences in psychiatric comorbidities and life adversities between patients with Rheumatoid arthritis + FM (secondary fibromyalgia [SFM]) and people with primary FM (PFM). In a cross\u2010sectional, observational study, patients with PFM and SFM underwent a structured interview for the lifetime diagnosis of major depression (MDD), panic disorder (PD) and post\u2010traumatic stress disorder (PTSD) and were assessed for childhood\/adulthood adversities and FM\u2010related symptoms severity. Thirty patients with PFM and 40 with SFM were recruited. The univariate analysis showed that the lifetime rates of MDD were significantly higher in PFM versus SFM (76.7 % and 40%, respectively, <jats:italic>p<\/jats:italic> &lt; 0.003), as well as the rates of PD (50 % and 15%, respectively, <jats:italic>p<\/jats:italic> &lt; 0.003), whereas there was no difference in PTSD rates. The rates of sexual abuse and physical neglect were significantly higher in PFM patients versus SFM patients (<jats:italic>p<\/jats:italic> &lt; 0.005 and <jats:italic>p<\/jats:italic> &lt; 0.023). Life events occurring before FM onset were different in PFM and SFM groups. In the logistic regression model, lifetime PD and physical neglect remain independent risk factors for PFM. PFM and SFM differ in psychiatric comorbidities and environmental adversities, suggesting that common pathogenesis may develop through different pathways.<\/jats:p>","DOI":"10.1002\/smi.2992","type":"journal-article","created":{"date-parts":[[2020,9,29]],"date-time":"2020-09-29T22:09:47Z","timestamp":1601417387000},"page":"255-262","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Differences in depression, anxiety and stress disorders between fibromyalgia associated with rheumatoid arthritis and primary fibromyalgia"],"prefix":"10.1002","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8971-4696","authenticated-orcid":false,"given":"Alessandra","family":"Alciati","sequence":"first","affiliation":[{"name":"Department of Clinical Neurosciences Hermanas Hospitalarias Villa S. Benedetto Menni Hospital  Albese (Como) Italy"},{"name":"Humanitas Clinical and Research Center IRCCS  Rozzano Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariateresa","family":"Cirillo","sequence":"additional","affiliation":[{"name":"Rheumatology Unit University of Messina  Messina Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ignazio Francesco","family":"Masala","sequence":"additional","affiliation":[{"name":"Trauma and Orthopedic Unit Santissima Trinit\u00e0 Hospital  Cagliari Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Piercarlo","family":"Sarzi\u2010Puttini","sequence":"additional","affiliation":[{"name":"Department of Rheumatology University Hospital ASST Fatebenefratelli Sacco  Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabiola","family":"Atzeni","sequence":"additional","affiliation":[{"name":"Rheumatology Unit University of Messina  Messina Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,10,6]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.berh.2015.04.018"},{"key":"e_1_2_6_3_1","first-page":"S99","article-title":"Is panic disorder associated with clinical severity of fibromyalgia? 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