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There is increasing evidence that self\u2010compassion might function as a buffer against the negative mental health effects of experiencing work\u2010stressors. However, while this moderating role of self\u2010compassion has been demonstrated when measures of subjective stress are used, different studies that use measures of more objective potential stressors failed to demonstrate a moderating role of self\u2010compassion. Furthermore, while cross\u2010sectional studies offer increasing support for this moderation effect of self\u2010compassion, few studies have examined this in longitudinal designs which may provide more robust insight into the role of self\u2010compassion on the relation between work stress experiences and symptoms of depression and anxiety. The aims of the current study were to examine whether self\u2010compassion moderates the concurrent and prospective association between a measure of potential work\u2010stressors and depressive and anxious symptomatology. The method consisted of a longitudinal survey study in a sample of 246 military personnel with three measurements, half a year apart from each other. Latent moderated structural equation modelling was conducted to test the potential moderating effect of self\u2010compassion. Self\u2010compassion was shown to significantly moderate the association between work\u2010stressors and depressive and anxiety symptomatology, both cross\u2010sectionally and prospectively after 6 and 12 months. Specifically, the experience of work\u2010stressors was positively associated with symptoms of depression and anxiety when self\u2010compassion was low and this association became weaker when self\u2010compassion was at a medium or high level. The results of the current study suggest that higher levels of work\u2010related stress covary more strongly with symptoms of depression and anxiety over time in personnel with lower levels of self\u2010compassion.<\/jats:p><\/jats:sec>","DOI":"10.1002\/smi.70006","type":"journal-article","created":{"date-parts":[[2025,1,31]],"date-time":"2025-01-31T16:49:56Z","timestamp":1738342196000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Work\u2010Stressors and Depression and Anxiety\u2014A Longitudinal Study of the Moderating Role of Self\u2010Compassion"],"prefix":"10.1002","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4959-5338","authenticated-orcid":false,"given":"E.","family":"de Krijger","sequence":"first","affiliation":[{"name":"Brain Research and Innovation Centre Ministry of Defence  Utrecht the Netherlands"},{"name":"Department of Psychology Health and Technoly Faculty of Behavioural, Management and Social Sciences University of Twente  Enschede the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2565-5439","authenticated-orcid":false,"given":"P. 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