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We examined prospective associations of COVID\u201019 pandemic\u2010related stressful events at baseline with mental health and sleep health at follow\u2010up using a population\u2010based cohort of Michigan adults with PCR\u2010confirmed COVID\u201019. We measured COVID\u201019\u2010related stressful events using the 6\u2010item Epidemic\u2010Pandemic Impacts Inventory (EPII), designed to assess pandemic impacts across personal and social life domains. We conducted (1) modified Poisson regression with robust standard errors for depressive symptoms, anxiety symptoms, COVID\u201019\u2010related post\u2010traumatic stress disorder (PTSD) symptoms, and poor\u2010to\u2010very poor sleep quality and (2) multinomial logistic regression for sleep duration (&lt;\u00a06, 6\u20139, &gt;\u00a09\u00a0h). We adjusted for sociodemographic, clinical, and survey factors. Our analytic samples were <jats:italic>n<\/jats:italic>\u00a0=\u00a03523 for mental health and <jats:italic>n<\/jats:italic>\u00a0=\u00a03191 for sleep health. Each additional COVID\u201019\u2010related stressful event reported was associated with a higher risk of reporting depressive symptoms (adjusted risk ratio [aRR]: 1.22, 95% confidence interval [CI]:1.14\u20131.30), anxiety symptoms (aRR: 1.20, 95% CI: 1.14\u20131.27) and COVID\u201019\u2010related PTSD symptoms (aRR: 1.31, 95% CI: 1.22\u20131.42). Each additional COVID\u201019\u2010related stressful event reported was also associated with a 1.13 times higher risk of reporting poor\u2010to\u2010very poor sleep quality (95% CI: 1.07\u20131.20). In the multinomial logistic regression models, stressful events were associated with a 1.21 (95% CI: 1.06\u20131.37) higher risk of sleeping &lt;\u00a06\u00a0h relative to sleeping 6\u20139\u00a0h. We need social support services and programs to improve psychological and behavioural responses to COVID\u201019\u2010related stressful events.<\/jats:p>","DOI":"10.1002\/smi.70044","type":"journal-article","created":{"date-parts":[[2025,5,2]],"date-time":"2025-05-02T15:10:52Z","timestamp":1746198652000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Prospective Associations of COVID\u201019 Pandemic\u2010Related Stressful Events With Mental and Sleep Health in a Population\u2010Based Cohort Study of Adults With SARS\u2010CoV\u20102 Infection"],"prefix":"10.1002","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0695-414X","authenticated-orcid":false,"given":"Soomin","family":"Ryu","sequence":"first","affiliation":[{"name":"Department of Epidemiology School of Public Health University of Michigan  Ann Arbor Michigan 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