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Data was collected from 2963 first\u2010year nursing students on four occasions over the course of their first semester of professional training (3 months). Four main profiles best described trajectories of alcohol\u2010related problems: High and Decreasing, Moderate and Stable, Moderate and Increasing, and Low and Stable. Our results suggested that initial (but not change in) levels of boredom, harassment, and alcohol use were primary drivers of these trajectories, reinforcing importance of early intervention. Initial levels of boredom and alcohol use were associated with a lower likelihood of membership into the Low and Stable profile relative to the other profiles. Boredom was also associated with higher initial levels of alcohol\u2010related problems in the High and Decreasing and Low and Stable profiles, while alcohol use was associated with membership into the Moderate and Stable profile relative to High and Decreasing and Moderate and Increasing profiles, as well as with higher initial levels and fluctuations over time in alcohol\u2010related problems in most profiles. Harassment was associated with higher initial levels of alcohol\u2010related problems in the Moderate and Stable profile, and with fluctuations in problems in the High and Decreasing and Moderate and Stable profiles. Profiles with lower levels of alcohol\u2010related problems tended to display lower levels of fatigue, and higher levels of perceived health and sleep quantity. Conversely, profiles with higher levels of alcohol\u2010related problems displayed poorer health outcomes. The person\u2010centred approach adopted in this study allows us to improve our understanding of how alcohol\u2010related problems first unfold among first\u2010year nursing students, as well as of the outcomes and predictors of these trajectories.<\/jats:p>","DOI":"10.1002\/smi.70162","type":"journal-article","created":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T05:04:42Z","timestamp":1773032682000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Trajectories of Alcohol\u2010Related Problems Among First\u2010Year Nursing Students: Nature, Predictors, and Outcomes"],"prefix":"10.1002","volume":"42","author":[{"given":"Pierre","family":"Cheyroux","sequence":"first","affiliation":[{"name":"QualiPsy UR 1901 Universit\u00e9 de Tours  Tours France"},{"name":"CHRU de Tours  Tours France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandre J. 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