{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T02:13:08Z","timestamp":1790820788578,"version":"4.1.0"},"reference-count":45,"publisher":"Wiley","issue":"15","license":[{"start":{"date-parts":[[2018,3,6]],"date-time":"2018-03-06T00:00:00Z","timestamp":1520294400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["51433003"],"award-info":[{"award-number":["51433003"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21504029"],"award-info":[{"award-number":["21504029"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81600823"],"award-info":[{"award-number":["81600823"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Small"],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Carbon dots with long\u2010wavelength emissions, high quantum yield (QY) and good biocompatibility are highly desirable for biomedical applications. Herein, a green, facile hydrothermal synthesis of highly efficient red emissive nitrogen\u2010doped carbonized polymer dots (CPDs) with optimal emission at around 630 nm are reported. The red emissive CPDs possess a variety of superior properties including excellent water dispersibility, good biocompatibility, narrow bandwidth emission, an excitation\u2010independent emission, and high QY (10.83% (in water) and 31.54% (in ethanol)). Further studies prove that such strong red fluorescence is ascribed to the efficient conjugated aromatic \u03c0 systems and hydrogen bonds of CPDs. And the fluorescence properties of CPDs can be regulated by adjusting the dosage of HNO\n                    <jats:sub>3<\/jats:sub>\n                    before the reaction. Additionally, the as\u2010prepared CPDs are successfully used as a fluorescent probe for bioimaging, both in vitro and in vivo. More importantly, biodistribution results demonstrate that most CPDs and their metabolites are not only excreted in urine but also excreted by hepatobiliary system in a rapid manner. Besides, the CPDs could easily cross the blood brain barrier, which may provide a valuable strategy for the theranostics of some brain diseases through real\u2010time tracking.\n                  <\/jats:p>","DOI":"10.1002\/smll.201703919","type":"journal-article","created":{"date-parts":[[2018,3,6]],"date-time":"2018-03-06T05:08:26Z","timestamp":1520312906000},"source":"Crossref","is-referenced-by-count":439,"title":["One\u2010Step Hydrothermal Synthesis of Nitrogen\u2010Doped Conjugated Carbonized Polymer Dots with 31% Efficient Red Emission for In Vivo Imaging"],"prefix":"10.1002","volume":"14","author":[{"given":"JunJun","family":"Liu","sequence":"first","affiliation":[{"name":"State Key Laboratory of Supramolecular Structure and Materials College of Chemistry Jilin University  Changchun 130012 P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daowei","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Oral Pathology College and Hospital of Stomatology Jilin University  Changchun 130012 P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai","family":"Zhang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Supramolecular Structure and Materials College of Chemistry Jilin University  Changchun 130012 P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingxi","family":"Yang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Supramolecular Structure and Materials College of Chemistry Jilin University  Changchun 130012 P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongchen","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Oral Pathology College and Hospital of Stomatology Jilin University  Changchun 130012 P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bai","family":"Yang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Supramolecular Structure and Materials College of Chemistry Jilin University  Changchun 130012 P. R. 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