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In general, the development of appropriate light\u2010triggered DDS relies on processes of photolysis, photoisomerization, photo\u2010cross\u2010linking\/un\u2010cross\u2010linking, and photoreduction, which are normally sensitive to ultraviolet (UV) or visible (Vis) light irradiation. Considering the issues of poor tissue penetration and high phototoxicity of these high\u2010energy photons of UV\/Vis light, recently nanocarriers have been developed based on light\u2010response to low\u2010energy photon irradiation, in particular for the light wavelengths located in the near infrared (NIR) range. NIR light\u2010triggered drug release systems are normally achieved by using two\u2010photon absorption and photon upconversion processes. Herein, recent advances of light\u2010responsive nanoplatforms for controlled drug release are reviewed, covering the mechanism of light responsive small molecules and polymers, UV and Vis light responsive nanocarriers, and NIR light responsive nanocarriers. NIR\u2010light triggered drug delivery by two\u2010photon excitation and upconversion luminescence strategies is also included. 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