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The present study leverages the intrinsically high surface\u2010to\u2010volume ratio as well as the mechanical robustness of nanostructures for obtaining highly\u2010sensitive detection of motion. To do so, highly\u2010aligned nanowires covering a large area were prepared by capillarity\u2010based mechanism. The nanowires exhibit a strain sensor with excellent gauge factor (\u224835.8), capable of high responses to various subtle external stimuli (\u2264200 \u00b5m deformation). The wearable strain sensor exhibits also a rapid response rate (\u2248230 ms), mechanical stability (1000 cycles) and reproducibility, low hysteresis (&lt;8.1%), and low power consumption (&lt;35 \u00b5W). Moreover, it achieves a gauge factor almost five times that of microwire\u2010based sensors. 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