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However, organ\u2010movement\u2010specific shape programing at a microscale level has never been demonstrated despite significant unmet needs. As vein\u2010to\u2010artery grafting induces vein dilation and stenosis, a polymeric self\u2010enclosable external support (SES) is designed to wrap the vascular out\u2010wall. Its micropores are programmed to increase sizes and interconnections upon dilation. Vessel dilation promotes venous maturation, but overdilation induces stenosis by disturbed blood flow. Therefore, the unique elastic shape\u2010fixity of SES provides a foundation to enable a stable microscale shape transition by maintaining the vein dilation. The shape transition of micropore architecture upon dilation induces beneficial inflammation, thereby regenerating vasa vasorum and directing smooth muscle cell migration toward adventitia with the consequent muscle reinforcement of veins. 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