{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T12:40:57Z","timestamp":1783600857503,"version":"3.55.0"},"reference-count":48,"publisher":"Wiley","issue":"50","license":[{"start":{"date-parts":[[2023,4,7]],"date-time":"2023-04-07T00:00:00Z","timestamp":1680825600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000015","name":"U.S. Department of Energy","doi-asserted-by":"publisher","award":["SC0022267"],"award-info":[{"award-number":["SC0022267"]}],"id":[{"id":"10.13039\/100000015","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006151","name":"Basic Energy Sciences","doi-asserted-by":"publisher","award":["SC0022267"],"award-info":[{"award-number":["SC0022267"]}],"id":[{"id":"10.13039\/100006151","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["1757371"],"award-info":[{"award-number":["1757371"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001309","name":"Research Corporation for Science Advancement","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001309","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Small"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Plants produce a wide range of bioactive phytochemicals, such as antioxidants and vitamins, which play crucial roles in aging prevention, inflammation reduction, and reducing the risk of cancer. Selectively harvesting these phytochemicals, such as lycopene, from tomatoes through the adsorption method is cost\u2010effective and energy efficient. In this work, a templated synthesis of 3D\u2010printed crosslinked cyclodextrin polymers featuring nanotubular structures for highly selective lycopene harvesting is reported. Polypseudorotaxanes formed by triethoxysilane\u2010based telechelic polyethylene glycols and \u03b1\u2010cyclodextrins (\u03b1\u2010CDs) are designed as the template to (1) synthetically access urethane\u2010based nanotubular structures at the molecular level, and (2) construct 3D\u2010printed architectures with designed macroscale voids. The polypseudorotaxane hydrogels showed good rheological properties for direct ink writing, and the 3D\u2010printed hydrogels\u00a0were\u00a0converted to the desired \u03b1\u2010CD polymer network through a three\u2010step postprinting transformation. The obtained urethane\u2010crosslinked \u03b1\u2010CD monoliths possess nanotubular structures and 3D\u2010printed voids. They selectively adsorb lycopene from raw tomato juice, protecting lycopene from photo\u2010 or thermo\u2010degradations. This work highlights the hierarchically templated synthesis approach in developing functional 3D\u2010printing materials by connecting the bottom\u2010up molecular assembly and synthesis with the top\u2010down 3D architecture control and fabrication.<\/jats:p>","DOI":"10.1002\/smll.202300323","type":"journal-article","created":{"date-parts":[[2023,4,8]],"date-time":"2023-04-08T03:59:35Z","timestamp":1680926375000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Hierarchically Templated Synthesis of 3D\u2010Printed Crosslinked Cyclodextrins for Lycopene Harvesting"],"prefix":"10.1002","volume":"19","author":[{"given":"Mingshi","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Chemistry Dartmouth College  41 College Street Hanover NH 03755 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenxing","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Chemistry Dartmouth College  41 College Street Hanover NH 03755 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qianming","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Chemistry Dartmouth College  41 College Street Hanover NH 03755 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4689-8923","authenticated-orcid":false,"given":"Chenfeng","family":"Ke","sequence":"additional","affiliation":[{"name":"Department of Chemistry Dartmouth College  41 College Street Hanover NH 03755 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,4,7]]},"reference":[{"key":"e_1_2_7_1_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-8223(97)00765-7"},{"key":"e_1_2_7_1_2","doi-asserted-by":"publisher","DOI":"10.1021\/jf071704w"},{"key":"e_1_2_7_1_3","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2019.01614"},{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1753-4887.1998.tb01691.x"},{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2010.05.055"},{"key":"e_1_2_7_2_3","doi-asserted-by":"publisher","DOI":"10.9734\/arrb\/2022\/v37i230490"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2011.12.025"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.2478\/s11696-013-0417-6"},{"key":"e_1_2_7_3_3","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodhyd.2015.07.017"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2017.01.157"},{"key":"e_1_2_7_4_2","doi-asserted-by":"crossref","unstructured":"b)P.Arora N.Dhingra Cyclodextrin: A Versatile Ingredient IntechOpen London 2018.","DOI":"10.5772\/intechopen.69187"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.198003441"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics11100545"},{"key":"e_1_2_7_5_3","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2022.112862"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.progpolymsci.2012.06.005"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/9781119247609"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-022-05032-1"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature16185"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.carbpol.2007.09.013"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1039\/C4TB00083H"},{"key":"e_1_2_7_9_3","doi-asserted-by":"publisher","DOI":"10.1039\/C9PY01679A"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/364516a0"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1143\/JJAP.40.L1327"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1063\/1.1334599"},{"key":"e_1_2_7_11_3","doi-asserted-by":"publisher","DOI":"10.1063\/1.1446423"},{"key":"e_1_2_7_11_4","doi-asserted-by":"publisher","DOI":"10.1021\/jp020817"},{"key":"e_1_2_7_11_5","doi-asserted-by":"publisher","DOI":"10.1021\/ma702040c"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201900469"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1039\/D0NR00291G"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1039\/D2CS01011A"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/1521-3927(20001101)21:17<1257::AID-MARC1257>3.0.CO;2-B"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1063\/1.480978"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chempr.2021.06.004"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1038\/nnano.2015.96"},{"key":"e_1_2_7_15_3","doi-asserted-by":"publisher","DOI":"10.1126\/science.abb3962"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1021\/la048970d"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1021\/ma050826r"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1021\/la9609231"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201900975"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201612440"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.1039\/C8TC02834F"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/356325a0"},{"key":"e_1_2_7_20_2","doi-asserted-by":"publisher","DOI":"10.1021\/cr970027"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1021\/cr970022c"},{"key":"e_1_2_7_21_2","first-page":"167","volume":"29","author":"Crini G.","year":"2022","journal-title":"Environ. Sci."},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac00042a016"},{"key":"e_1_2_7_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0963-9969(99)00059-9"},{"key":"e_1_2_7_22_3","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.9b06669"}],"container-title":["Small"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/am-pdf\/10.1002\/smll.202300323","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/smll.202300323","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,28]],"date-time":"2023-12-28T09:43:01Z","timestamp":1703756581000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/smll.202300323"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,7]]},"references-count":48,"journal-issue":{"issue":"50","published-print":{"date-parts":[[2023,12]]}},"alternative-id":["10.1002\/smll.202300323"],"URL":"https:\/\/doi.org\/10.1002\/smll.202300323","archive":["Portico"],"relation":{},"ISSN":["1613-6810","1613-6829"],"issn-type":[{"value":"1613-6810","type":"print"},{"value":"1613-6829","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,4,7]]},"assertion":[{"value":"2023-01-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-04-07","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"2300323"}}