{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T02:40:01Z","timestamp":1782441601510,"version":"3.54.5"},"reference-count":40,"publisher":"Wiley","issue":"22","license":[{"start":{"date-parts":[[2023,2,24]],"date-time":"2023-02-24T00:00:00Z","timestamp":1677196800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["51971116"],"award-info":[{"award-number":["51971116"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Small"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Nanoheterostructures with exquisite interface and heterostructure design find numerous applications in catalysis, plasmonics, electronics, and biomedicine. In the current study, series core\u2013shell metal or metal oxide\u2010based heterogeneous nanocomposite have been successfully fabricated by employing sandwiched liquid metal (LM) layer (i.e., LM oxide\/LM\/LM oxide) as interfacial galvanic replacement reaction environment. A self\u2010limiting thin oxide layer, which would naturally occur at the metal\u2013air interface under ambient conditions, could be readily delaminated onto the surface of core metal (Fe, Bi, carbonyl iron, Zn, Mo) or metal oxide (Fe<jats:sub>3<\/jats:sub>O<jats:sub>4<\/jats:sub>, Fe<jats:sub>2<\/jats:sub>O<jats:sub>3<\/jats:sub>, MoO<jats:sub>3<\/jats:sub>, ZrO<jats:sub>2<\/jats:sub>, TiO<jats:sub>2<\/jats:sub>) nano\u2010 or micro\u2010particles by van der Waals (vdW) exfoliation. Further on, the sandwiched LM layer could be formed immediately and acted as the reaction site of galvanic replacement where metals (Au, Ag, and Cu) or metal oxide (MnO<jats:sub>2<\/jats:sub>) with higher reduction potential could be deposited as shell structure. Such strategy provides facile and versatile approaches to design and fabricate nanoheterostructures. As a model, nanocomposite of Fe@Sandwiched\u2010GaIn\u2010Au (Fe@SW\u2010GaIn\u2010Au) is constructed and their application in targeted magnetic resonance imaging (MRI) guided photothermal tumor ablation and chemodynamic therapy (CDT), as well as the enhanced radiotherapy\u00a0(RT) against tumors, have been systematically investigated.<\/jats:p>","DOI":"10.1002\/smll.202300751","type":"journal-article","created":{"date-parts":[[2023,2,25]],"date-time":"2023-02-25T03:32:27Z","timestamp":1677295947000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Nanoheterostructure by Liquid Metal Sandwich\u2010Based Interfacial Galvanic Replacement for Cancer Targeted Theranostics"],"prefix":"10.1002","volume":"19","author":[{"given":"Zhenhu","family":"Guo","sequence":"first","affiliation":[{"name":"State Key Laboratory of New Ceramics and Fine Processing School of Materials Science and Engineering Tsinghua University  Beijing 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