{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T17:55:38Z","timestamp":1789581338047,"version":"build-2803163510"},"reference-count":83,"publisher":"Wiley","issue":"44","license":[{"start":{"date-parts":[[2024,7,14]],"date-time":"2024-07-14T00:00:00Z","timestamp":1720915200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Small"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>This study focuses on designing and evaluating scaffolds with essential properties for bone regeneration, such as biocompatibility, macroporous geometry, mechanical strength, and magnetic responsiveness. The scaffolds are made using 3D printing with acrylic resin and iron oxides synthesized through solution combustion. Utilizing triply periodic minimal surfaces (TPMS) geometry and mask stereolithography (MSLA) printing, the scaffolds achieve precise geometrical features. The mechanical properties are enhanced through resin curing, and magnetite particles from synthesized nanoparticles and alluvial magnetite are added for magnetic properties. The scaffolds show a balance between stiffness, porosity, and magnetic responsiveness, with maximum compression strength between 4.8 and 9.2 MPa and Young's modulus between 58 and 174 MPa. Magnetic properties such as magnetic coercivity, remanence, and saturation are measured, with the best results from scaffolds containing synthetic iron oxides at 1% weight. The viscosity of the mixtures used for printing is between 350 and 380 mPas, and contact angles between 90\u00b0 and 110\u00b0 are achieved. Biocompatibility tests indicate the potential for clinical trials, though further research is needed to understand the impact of magnetic properties on cellular interactions and optimize scaffold design for specific applications. This integrated approach offers a promising avenue for the development of advanced materials capable of promoting enhanced bone regeneration.<\/jats:p>","DOI":"10.1002\/smll.202402419","type":"journal-article","created":{"date-parts":[[2024,7,15]],"date-time":"2024-07-15T01:12:33Z","timestamp":1721005953000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Utilization of Additive Manufacturing Techniques for the Development of a Novel Scaffolds with Magnetic Properties for Potential Application in Enhanced Bone Regeneration"],"prefix":"10.1002","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6317-6172","authenticated-orcid":false,"given":"Yeison Alejandro","family":"Orozco\u2010Osorio","sequence":"first","affiliation":[{"name":"Universidad Nacional de Colombia sede Medell\u00edn  Carrera 65 # 59A\u2010100 Medellin Antioquia 050034 Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela Victoria","family":"Gaita\u2010Anturi","sequence":"additional","affiliation":[{"name":"Universidad de Antioquia  Calle 70 # 52\u201021, 1226 Medell\u00edn 050010 Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia Patricia","family":"Ossa\u2010Orozco","sequence":"additional","affiliation":[{"name":"Universidad de Antioquia  Calle 70 # 52\u201021, 1226 Medell\u00edn 050010 Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda","family":"Arias\u2010Acevedo","sequence":"additional","affiliation":[{"name":"Instituto Tecnol\u00f3gico Metropolitano  Calle 73 #76A\u2010354, Campus Robledo Medell\u00edn Antioquia 50034 Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diego","family":"Uribe","sequence":"additional","affiliation":[{"name":"Instituto Tecnol\u00f3gico Metropolitano  Calle 73 #76A\u2010354, Campus Robledo Medell\u00edn Antioquia 50034 Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Paucar","sequence":"additional","affiliation":[{"name":"Universidad Nacional de Colombia sede Medell\u00edn  Carrera 65 # 59A\u2010100 Medellin Antioquia 050034 Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andres Felipe","family":"Vasquez","sequence":"additional","affiliation":[{"name":"New Stetic  Cra. 53 #50\u201009 Guarne Antioquia 054050 Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wilmer","family":"Saldarriaga","sequence":"additional","affiliation":[{"name":"Universidad Nacional de Colombia sede Medell\u00edn  Carrera 65 # 59A\u2010100 Medellin Antioquia 050034 Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Gabriel","family":"Ramirez","sequence":"additional","affiliation":[{"name":"Universidad de los Andes  Bogot\u00e1 Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex","family":"Lopera","sequence":"additional","affiliation":[{"name":"Grupo de Nanoestructuras y F\u00edsica Aplicada (NANOUPAR) Universidad Nacional de Colombia  La Paz 202017 Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8241-9969","authenticated-orcid":false,"given":"Claudia","family":"Garc\u00eda","sequence":"additional","affiliation":[{"name":"Universidad Nacional de Colombia sede Medell\u00edn  Carrera 65 # 59A\u2010100 Medellin Antioquia 050034 Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,7,14]]},"reference":[{"key":"e_1_2_8_1_1","volume-title":"The Human Bone Manual","author":"White T. D.","year":"2005"},{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.injury.2006.04.130"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/1741-7015-9-66"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics11080393"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph18030894"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mtbio.2020.100067"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2019.00268"},{"key":"e_1_2_8_8_1","first-page":"S100","volume":"66","author":"Bourd\u00f3n\u2010Santoyo M.","year":"2014","journal-title":"Rev. Invest. Clin."},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.0c05122"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10856-020-06364-y"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22031128"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.engreg.2021.09.004"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.3390\/ma17030654"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.3390\/sym10090361"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsamd.2020.01.007"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.18063\/ijb.v6i2.265"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eurpolymj.2020.109870"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.irbm.2020.05.007"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.3390\/polym13010159"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.carbpol.2021.118603"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.msec.2018.11.088"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcis.2021.06.067"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.matchemphys.2021.125302"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.msec.2020.111752"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2019.05.070"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ceramint.2019.04.113"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmst.2020.04.037"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.msec.2021.112287"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.msec.2020.111056"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.3390\/jfb10030030"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2021.629270"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2020.00793"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.202001232"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.matchemphys.2020.123642"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2021.05.215"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bprint.2021.e00167"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2021.05.007"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1007\/s42242-020-00109-0"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40824-021-00204-y"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.reth.2021.01.007"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12938-020-00810-2"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2021.121037"},{"key":"e_1_2_8_43_1","volume":"2022","author":"Zhang Q.","year":"2022","journal-title":"Research"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2020.586406"},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2020.129003"},{"key":"e_1_2_8_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prosdent.2019.05.002"},{"key":"e_1_2_8_47_1","doi-asserted-by":"publisher","DOI":"10.3390\/pr8091138"},{"key":"e_1_2_8_48_1","doi-asserted-by":"publisher","DOI":"10.1039\/C9PY01445D"},{"key":"e_1_2_8_49_1","doi-asserted-by":"publisher","DOI":"10.1080\/14686996.2018.1471653"},{"key":"e_1_2_8_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ceramint.2019.11.282"},{"key":"e_1_2_8_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2019.122928"},{"key":"e_1_2_8_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmt.2019.05.005"},{"key":"e_1_2_8_53_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11665-021-06067-7"},{"key":"e_1_2_8_54_1","doi-asserted-by":"publisher","DOI":"10.15541\/jim20160628"},{"key":"e_1_2_8_55_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.0c13851"},{"key":"e_1_2_8_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2017.03.006"},{"key":"e_1_2_8_57_1","first-page":"ZF01","volume":"10","author":"Gujjalapudi M.","year":"2016","journal-title":"JCDR"},{"key":"e_1_2_8_58_1","doi-asserted-by":"publisher","DOI":"10.1590\/1678-775720150336"},{"key":"e_1_2_8_59_1","doi-asserted-by":"publisher","DOI":"10.1002\/bem.21903"},{"key":"e_1_2_8_60_1","doi-asserted-by":"publisher","DOI":"10.1080\/15368378.2018.1458626"},{"key":"e_1_2_8_61_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12011-017-1161-5"},{"key":"e_1_2_8_62_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00264-009-0932-9"},{"key":"e_1_2_8_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2019.122694"},{"key":"e_1_2_8_64_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0091584"},{"key":"e_1_2_8_65_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.b.33836"},{"key":"e_1_2_8_66_1","doi-asserted-by":"publisher","DOI":"10.1039\/C4RA12640H"},{"key":"e_1_2_8_67_1","doi-asserted-by":"publisher","DOI":"10.1088\/0957-4484\/22\/1\/015104"},{"key":"e_1_2_8_68_1","doi-asserted-by":"publisher","DOI":"10.1063\/1.4812323"},{"key":"e_1_2_8_69_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmbbm.2020.104254"},{"key":"e_1_2_8_70_1","unstructured":"International Organization for Standarization (ISO).Biological evaluation of medical devices Part 5: Tests for in vitro cytotoxicity. ISO 10993\u20105 2009."},{"key":"e_1_2_8_71_1","unstructured":"International Organization for Standarization (ISO).Biological evaluation of medical devices. Part 12: Sample preparation and reference materials. ISO 10993\u201012 2021."},{"key":"e_1_2_8_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ceramint.2017.12.004"},{"key":"e_1_2_8_73_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-323-35386-1.00004-9"},{"key":"e_1_2_8_74_1","doi-asserted-by":"publisher","DOI":"10.1039\/D3PY00261F"},{"key":"e_1_2_8_75_1","doi-asserted-by":"publisher","DOI":"10.1080\/10236669608033358"},{"key":"e_1_2_8_76_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-817590-3.00002-6"},{"key":"e_1_2_8_77_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmats.2019.00268"},{"key":"e_1_2_8_78_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prosdent.2019.05.034"},{"key":"e_1_2_8_79_1","doi-asserted-by":"publisher","DOI":"10.4321\/S1889-836X2013000200007"},{"key":"e_1_2_8_80_1","first-page":"43","volume-title":"Membrane Technology for Sustainable Water and Energy Management","author":"Jeong S.","year":"2023"},{"key":"e_1_2_8_81_1","doi-asserted-by":"publisher","DOI":"10.1080\/03008207.2018.1499732"},{"key":"e_1_2_8_82_1","doi-asserted-by":"publisher","DOI":"10.1039\/C9TB02309G"},{"key":"e_1_2_8_83_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejps.2010.09.001"}],"container-title":["Small"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/smll.202402419","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,14]],"date-time":"2025-01-14T02:10:50Z","timestamp":1736820650000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/smll.202402419"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,14]]},"references-count":83,"journal-issue":{"issue":"44","published-print":{"date-parts":[[2024,11]]}},"alternative-id":["10.1002\/smll.202402419"],"URL":"https:\/\/doi.org\/10.1002\/smll.202402419","archive":["Portico"],"relation":{},"ISSN":["1613-6810","1613-6829"],"issn-type":[{"value":"1613-6810","type":"print"},{"value":"1613-6829","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7,14]]},"assertion":[{"value":"2024-03-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-07-14","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"2402419"}}