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However, most current pharmacological strategies face challenges related to non\u2010specific delivery, leading to significant side effects that hinder safe and effective treatments. To address these issues, galactose\u2010functionalized amphiphiles are synthesized that can self\u2010assemble into micelles and be loaded with a senolytic cargo. These galactose\u2010micelles are responsive to the lysosomal \u03b2\u2010galactosidase enzyme, present in elevated amounts in senescent cells, and are employed for specific delivery of the senolytic Bcl2\u2010inhibitor Navitoclax. 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