{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T00:35:49Z","timestamp":1788395749139,"version":"build-2803163510"},"reference-count":104,"publisher":"Wiley","issue":"16","license":[{"start":{"date-parts":[[2025,3,17]],"date-time":"2025-03-17T00:00:00Z","timestamp":1742169600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,3,17]],"date-time":"2025-03-17T00:00:00Z","timestamp":1742169600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100007857","name":"Stiftelsen Konung Gustaf V:s 80-\u00e5rsfond","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007857","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004359","name":"Vetenskapsr\u00e5det","doi-asserted-by":"publisher","award":["2022\u201000561"],"award-info":[{"award-number":["2022\u201000561"]}],"id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["KL3012\/4\u20101"],"award-info":[{"award-number":["KL3012\/4\u20101"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["RO2414\/12\u20101"],"award-info":[{"award-number":["RO2414\/12\u20101"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["STA1282\/8\u20101"],"award-info":[{"award-number":["STA1282\/8\u20101"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["STR\u00a0666\/10\u20101"],"award-info":[{"award-number":["STR\u00a0666\/10\u20101"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005760","name":"G\u00f6teborgs Universitet","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005760","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Small"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Migrastatic drugs targeting cell motility and suppressing invasiveness of solid tumors, have the potential to bring about a paradigm shift in the treatment of solid cancer. Cytochalasin B (\n                    <jats:bold>CB<\/jats:bold>\n                    ) is a potent migrastatic compound, but its clinical use is limited by poor selectivity. Here, a NQO1\u2010responsive prodrug,\n                    <jats:bold>BQTML\u2010CB<\/jats:bold>\n                    is developed, synthesized in three steps from cytochalasin B derived from\n                    <jats:italic>Preussia similis<\/jats:italic>\n                    G22.\n                    <jats:bold>BQTML\u2010CB<\/jats:bold>\n                    is selectively activated in NQO1\u2010positive cancer cells, releasing active\n                    <jats:bold>CB<\/jats:bold>\n                    .\n                    <jats:italic>In vitro<\/jats:italic>\n                    ,\n                    <jats:bold>BQTML\u2010CB<\/jats:bold>\n                    significantly inhibits proliferation and migration in NQO1\u2010positive U\u20102OS cells, causing actin disruption and cytokinesis abnormalities, while sparing NQO1\u2010negative B16\u2010F1 cells. The prodrug shows reduced effects on human neutrophils, indicating reduced immunosuppressive activity of\n                    <jats:bold>BQTML\u2010CB<\/jats:bold>\n                    compared to\n                    <jats:bold>CB<\/jats:bold>\n                    . Co\u2010culture studies reveal a beneficial bystander effect, as cleaved\n                    <jats:bold>CB<\/jats:bold>\n                    diffused into adjacent NQO1\u2010deficient cells. These findings support\n                    <jats:bold>BQTML\u2010CB<\/jats:bold>\n                    as a cancer\u2010targeted prodrug with selective antiproliferative and migrastatic properties, highlighting the potential of C7\u2010OH\u2010modified cytochalasans in cancer therapy.\n                  <\/jats:p>","DOI":"10.1002\/smll.202410861","type":"journal-article","created":{"date-parts":[[2025,3,17]],"date-time":"2025-03-17T06:30:51Z","timestamp":1742193051000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["NQO1\u2010Responsive Prodrug for\n                    <i>in Cellulo<\/i>\n                    Release of Cytochalasin B as Cancer Cell\u2010Targeted Migrastatic"],"prefix":"10.1002","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3714-7738","authenticated-orcid":false,"given":"Mervic D.","family":"Kagho","sequence":"first","affiliation":[{"name":"Department of Chemistry and Molecular Biology Division of Organic and Medicinal Chemistry University of Gothenburg  Natrium, Medicinaregatan 7B Gothenburg 413 90 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1512-1748","authenticated-orcid":false,"given":"Katharina","family":"Schmidt","sequence":"additional","affiliation":[{"name":"Department of Cell Biology Helmholtz Centre for Infection Research  Inhoffenstrasse 7 38124 Braunschweig Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Lambert","sequence":"additional","affiliation":[{"name":"Department of Cell Biology Helmholtz Centre for Infection Research  Inhoffenstrasse 7 38124 Braunschweig Germany"},{"name":"Division of Molecular Cell Biology Zoological Institute Technische Universit\u00e4t Braunschweig  Spielmannstrasse 7 38106 Braunschweig Germany"},{"name":"Department of Microbial Drugs Helmholtz Centre for Infection Research  Inhoffenstrasse 7 38124 Braunschweig Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lili","family":"Jia","sequence":"additional","affiliation":[{"name":"Department of Microbial Drugs Helmholtz Centre for Infection Research  Inhoffenstrasse 7 38124 Braunschweig Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5671-1547","authenticated-orcid":false,"given":"Vignesh","family":"Venkatakrishnan","sequence":"additional","affiliation":[{"name":"Department of Life Sciences Chalmers University of Technology  Kemiv\u00e4gen 4 G\u00f6teborg 41296 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luisa","family":"Mehr","sequence":"additional","affiliation":[{"name":"Department of Cell Biology Helmholtz Centre for Infection Research  Inhoffenstrasse 7 38124 Braunschweig Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9094-6478","authenticated-orcid":false,"given":"Johan","family":"Bylund","sequence":"additional","affiliation":[{"name":"Department of Oral Microbiology and Immunology Institute of Odontology Sahlgrenska Academy University of Gothenburg  Medicinaregatan 12F G\u00f6teborg 413 90 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4244-4198","authenticated-orcid":false,"given":"Klemens","family":"Rottner","sequence":"additional","affiliation":[{"name":"Department of Cell Biology Helmholtz Centre for Infection Research  Inhoffenstrasse 7 38124 Braunschweig Germany"},{"name":"Division of Molecular Cell Biology Zoological Institute Technische Universit\u00e4t Braunschweig  Spielmannstrasse 7 38106 Braunschweig Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7284-8671","authenticated-orcid":false,"given":"Marc","family":"Stadler","sequence":"additional","affiliation":[{"name":"Department of Microbial Drugs Helmholtz Centre for Infection Research  Inhoffenstrasse 7 38124 Braunschweig Germany"},{"name":"Institute for Microbiology Technische Universit\u00e4t Braunschweig  Spielmannstra\u00dfe 7 38106 Braunschweig Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0352-9474","authenticated-orcid":false,"given":"Theresia E. B.","family":"Stradal","sequence":"additional","affiliation":[{"name":"Department of Cell Biology Helmholtz Centre for Infection Research  Inhoffenstrasse 7 38124 Braunschweig Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4713-2345","authenticated-orcid":false,"given":"Philipp","family":"Klahn","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Molecular Biology Division of Organic and Medicinal Chemistry University of Gothenburg  Natrium, Medicinaregatan 7B Gothenburg 413 90 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,3,17]]},"reference":[{"key":"e_1_2_8_1_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21660"},{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.exphem.2014.07.268"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.959840"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.2474"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-020-0134-x"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trecan.2017.04.008"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1039\/C5OB02272J"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1039\/D3MD00535F"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1039\/p19730001146"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trecan.2019.10.011"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-981-16-5422-0_266"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbcan.2014.09.007"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-015-1619-9"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trecan.2023.01.001"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-030-32857-3_9"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.206433"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.197303701"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11557-017-1288-y"},{"key":"e_1_2_8_19_1","volume":"2","author":"Stadler M.","year":"2007","journal-title":"Nat. Prod. Commun."},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1039\/C7NP00036G"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1039\/b903913a"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1021\/cr050001f"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.3390\/biom8040129"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.3390\/biom9020073"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.3390\/biom13081247"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.2174\/1871520614666141016164335"},{"key":"e_1_2_8_27_1","first-page":"1431","volume":"50","author":"Bousquet P. F.","year":"1990","journal-title":"Cancer Res."},{"key":"e_1_2_8_28_1","first-page":"2719","volume":"38","author":"Steiner M. R.","year":"1978","journal-title":"Cancer Res."},{"key":"e_1_2_8_29_1","first-page":"329","volume":"40","author":"Medina D.","year":"1980","journal-title":"Cancer Res."},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01741335"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10637-014-0203-5"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/tera.1420350112"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1603735113"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.176.4042.1432"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)63372-7"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi00545a011"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0024-3205(99)00590-1"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1002\/cbic.201900544"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.4155\/fmc-2021-0289"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells13151272"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2019.07.017"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.8b00124"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.1038\/s43018-023-00554-7"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41388-022-02477-6"},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja00492a082"},{"key":"e_1_2_8_46_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja00354a072"},{"key":"e_1_2_8_47_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0402111101"},{"key":"e_1_2_8_48_1","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201602439"},{"key":"e_1_2_8_49_1","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201603734"},{"key":"e_1_2_8_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tet.2011.09.079"},{"key":"e_1_2_8_51_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201809703"},{"key":"e_1_2_8_52_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.8b01768"},{"key":"e_1_2_8_53_1","doi-asserted-by":"publisher","DOI":"10.1039\/a906412e"},{"key":"e_1_2_8_54_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0039-1691500"},{"key":"e_1_2_8_55_1","doi-asserted-by":"publisher","DOI":"10.1039\/c39860001447"},{"key":"e_1_2_8_56_1","doi-asserted-by":"publisher","DOI":"10.1039\/p19890000525"},{"key":"e_1_2_8_57_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja00203a042"},{"key":"e_1_2_8_58_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja00328a053"},{"key":"e_1_2_8_59_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja00222a047"},{"key":"e_1_2_8_60_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200290057"},{"key":"e_1_2_8_61_1","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201804023"},{"key":"e_1_2_8_62_1","doi-asserted-by":"publisher","DOI":"10.1039\/c39860000727"},{"key":"e_1_2_8_63_1","doi-asserted-by":"publisher","DOI":"10.1039\/c39900000464"},{"key":"e_1_2_8_64_1","doi-asserted-by":"publisher","DOI":"10.1039\/D2QO01223E"},{"key":"e_1_2_8_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tchem.2022.100022"},{"key":"e_1_2_8_66_1","unstructured":"H.Zhu C.Chen Q.Tong Y.Zhou Y.Ye L.Gu Y.Zhang inProgress in the Chemistry of Organic Natural Products (Eds.:A.Kinghorn H.Falk S.Gibbons Y.Asakawa J.\u2010K.Liu V. M.Dirsch) Springer Cham 2021 pp.1\u2010134."},{"key":"e_1_2_8_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chempr.2020.11.010"},{"key":"e_1_2_8_68_1","doi-asserted-by":"publisher","DOI":"10.3762\/bjoc.9.243"},{"key":"e_1_2_8_69_1","doi-asserted-by":"publisher","DOI":"10.1080\/00275514.2023.2188868"},{"key":"e_1_2_8_70_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fitote.2023.105434"},{"key":"e_1_2_8_71_1","doi-asserted-by":"publisher","DOI":"10.1002\/chem.202002241"},{"key":"e_1_2_8_72_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.9b01344"},{"key":"e_1_2_8_73_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jnatprod.4c00676"},{"key":"e_1_2_8_74_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2008.09.082"},{"key":"e_1_2_8_75_1","unstructured":"R. V.Nair S.Zhao E.Terriac F.Lautenschl\u00e4ger J. H. R.Hetmanski P. T.Caswell A.delCampo ChemRxiv2020 10.26434\/chemrxiv.12609545.v1."},{"key":"e_1_2_8_76_1","doi-asserted-by":"publisher","DOI":"10.1002\/cbic.201800269"},{"key":"e_1_2_8_77_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-11238-1"},{"key":"e_1_2_8_78_1","doi-asserted-by":"publisher","DOI":"10.1002\/chem.202103525"},{"key":"e_1_2_8_79_1","doi-asserted-by":"publisher","DOI":"10.1002\/chem.202403486"},{"key":"e_1_2_8_80_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja062012b"},{"key":"e_1_2_8_81_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.97.7.3177"},{"key":"e_1_2_8_82_1","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.103.050070"},{"key":"e_1_2_8_83_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0076-6879(04)82009-3"},{"key":"e_1_2_8_84_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00343960"},{"key":"e_1_2_8_85_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.69.2.442"},{"key":"e_1_2_8_86_1","first-page":"3","volume":"294","author":"Webb D. J.","year":"2005","journal-title":"Methods Mol. Biol."},{"key":"e_1_2_8_87_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jid.2016.11.020"},{"key":"e_1_2_8_88_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-0716-0154-9_22"},{"key":"e_1_2_8_89_1","doi-asserted-by":"publisher","DOI":"10.1111\/eci.12951"},{"key":"e_1_2_8_90_1","doi-asserted-by":"publisher","DOI":"10.1189\/jlb.0905498"},{"key":"e_1_2_8_91_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcb.240270306"},{"key":"e_1_2_8_92_1","doi-asserted-by":"publisher","DOI":"10.1111\/cmi.13348"},{"key":"e_1_2_8_93_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-44111-8"},{"key":"e_1_2_8_94_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrclinonc.2017.166"},{"key":"e_1_2_8_95_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11912-022-01266-4"},{"key":"e_1_2_8_96_1","doi-asserted-by":"publisher","DOI":"10.1124\/dmd.121.000503"},{"key":"e_1_2_8_97_1","doi-asserted-by":"publisher","DOI":"10.3390\/biom9020073"},{"key":"e_1_2_8_98_1","doi-asserted-by":"publisher","DOI":"10.3390\/jof7020131"},{"key":"e_1_2_8_99_1","author":"Branda N.","year":"2019","journal-title":"JoVE Sci. Educ. Database. Org. Chem."},{"key":"e_1_2_8_100_1","doi-asserted-by":"publisher","DOI":"10.1021\/jo00408a041"},{"key":"e_1_2_8_101_1","unstructured":"C. C.Jimidar C. S. G.Ganskow M. D.Kagho A.Chakrabarti M.Zollo U.Beutling L. C.Cesar J.Morud M.Br\u00f6nstrup S. A.Sieber S. M.Hacker P.Klahn ChemRxiv2024 10.26434\/chemrxiv\u20102024\u2010f8\u00d78z\u2010v2."},{"key":"e_1_2_8_102_1","doi-asserted-by":"publisher","DOI":"10.3390\/biom10050805"},{"key":"e_1_2_8_103_1","doi-asserted-by":"publisher","DOI":"10.26434\/chemrxiv\u20102025\u20106xhv5"},{"key":"e_1_2_8_104_1","doi-asserted-by":"publisher","DOI":"10.1087\/20150211"}],"container-title":["Small"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/smll.202410861","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/smll.202410861","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/smll.202410861","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T10:12:50Z","timestamp":1774865570000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/smll.202410861"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,17]]},"references-count":104,"journal-issue":{"issue":"16","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["10.1002\/smll.202410861"],"URL":"https:\/\/doi.org\/10.1002\/smll.202410861","archive":["Portico"],"relation":{"has-preprint":[{"id-type":"doi","id":"10.26434\/chemrxiv-2024-srxfv","asserted-by":"object"}]},"ISSN":["1613-6810","1613-6829"],"issn-type":[{"value":"1613-6810","type":"print"},{"value":"1613-6829","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,17]]},"assertion":[{"value":"2024-11-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-03-17","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"2410861"}}