{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:56:00Z","timestamp":1786978560248,"version":"build-2736575974"},"reference-count":53,"publisher":"Wiley","issue":"18","license":[{"start":{"date-parts":[[2025,1,7]],"date-time":"2025-01-07T00:00:00Z","timestamp":1736208000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,1,7]],"date-time":"2025-01-07T00:00:00Z","timestamp":1736208000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Small"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Cells perceive external and internally generated forces of different kinds, significantly impacting their cellular biology. In the relatively nascent field of mechanobiology, the impact of such forces is studied and further utilized to broaden the knowledge of cellular developmental pathways, disease progression, tissue engineering, and developing novel regenerative strategies. However, extensive considerations of mechanotransduction pathways for biomedical applications are still broadly limited due to a lack of affordable technologies in terms of devices and simple magnetic actuatable materials. Herein, synthesizing a monophasic, macroporous, in situ\u2010fabricated gelatin\u2010based ferrogel is reported using polyethylene glycol (PEG) coated\u2010iron oxide (magnetite) particles with high magnetization. Developing a 3D printed, compact, and wireless device capable of providing a wide range of magneto\u2010mechanical actuation using magnetic field susceptible materials in a noncontact manner is reported. Using the device and ferrogel, C2C12 myoblast differentiation is studied under magnetic field actuation, and significant differences in the myogenin, a differentiation marker, expression behavior are observed. Due to careful design considerations, robust component selection, and easy availability of\u00a0low\u2010cost precursor for magnetic responsive material fabrication, the device\u2010ferrogel combination can be easily adapted to routine biological studies, thereby helping mechanobiology to be utilized for developing exciting new biomedical strategies.<\/jats:p>","DOI":"10.1002\/smll.202412112","type":"journal-article","created":{"date-parts":[[2025,1,8]],"date-time":"2025-01-08T02:21:06Z","timestamp":1736302866000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Impact of Magneto\u2010Mechanical Actuation on Cell Differentiation: A Study Using Wireless, 3D\u2010Printed Device and a Porous Ferrogel"],"prefix":"10.1002","volume":"21","author":[{"given":"Soumyadeep","family":"Basak","sequence":"first","affiliation":[{"name":"Department of Biosciences and Bioengineering Indian Institute of Technology Roorkee  Roorkee Uttarakhand 247667 India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1379-1203","authenticated-orcid":false,"given":"Gopinath","family":"Packirisamy","sequence":"additional","affiliation":[{"name":"Department of Biosciences and Bioengineering Indian Institute of Technology Roorkee  Roorkee Uttarakhand 247667 India"},{"name":"Centre for Nanotechnology Indian Institute of Technology Roorkee  Roorkee Uttarakhand 247667 India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,1,7]]},"reference":[{"key":"e_1_2_8_1_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrm.2017.108"},{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-023-01501-9"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrm.2017.87"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21155399"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mser.2015.04.001"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41427-018-0100-z"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsabm.9b00580"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsbiomaterials.8b00240"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/smtd.202100276"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cobme.2023.100449"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2018.01.049"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202312497"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioactmat.2022.12.019"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2021.130398"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsbiomaterials.1c00459"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202300017"},{"key":"e_1_2_8_17_1","doi-asserted-by":"crossref","unstructured":"V. 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